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d galactosamine/sarcoma
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Eosinophilic globule cells in mouse MFH-like sarcomas: lectin histochemistry.
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Lectin binding patterns in ten mouse malignant fibrous histiocytoma (MFH)-like sarcomas containing eosinophilic globule (EG) cells and in granular metrial gland (GMG) cells of mouse placenta were stained with nine lectins (Con A, LCA, WGA, DBA, SBA, e-PHA, PNA, RCA-I and UEA-I) by an
Elucidation of similarities of sugar receptor (lectin) expression of human lung metastases from histogenetically different types of primary tumors.
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Selective interplay between proteins and carbohydrates of cellular glycoconjugates offers the potential to mediate physiologically important biorecognition and biosignaling, relevant to metastasis formation. Biotinylated neoglycoproteins were therefore employed as tools to detect endogenous sugar
A C-terminal carbohydrate-binding domain in the endothelial cell regulatory protein, pigpen: new function for an EWS family member.
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The potential for encoding information in carbohydrate (CHO) structures has long been recognized. Selective CHO-binding proteins known as lectins and the biological events they mediate are well known. However, many lectins were originally discovered for biological activities other than saccharide
Hepatocellular injury inhibits lectin-mediated tumor colonization into BALB/c-mice livers.
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Acute (hepatitis) and chronic (cirrhosis) liver injuries were experimentally induced in BALB/c-mice by administration of D-galactosamine and carbon tetrachloride, respectively. In both experimental liver diseases the incidence of hepatic tumor colonization of sarcoma L-1 was significantly reduced as
Identification of adult hepatic progenitor cells capable of repopulating injured rat liver.
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Oval cells appear and expand in the liver when hepatocyte proliferation is compromised. Many different markers have been attributed to these cells, but their nature still remains obscure. This study is a detailed gene expression analysis aimed at revealing their identity and repopulating in vivo
Helix pomatia agglutinin binding in human tumour cell lines: correlation with pulmonary metastases in nude mice.
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The extent of lectin binding by three human melanoma (LOX, FEMX-1 and SESX) and two sarcoma lines (MHMX and OHSX) was related to their potential for experimental metastasis formation in athymic nude mice. The Helix pomatia agglutinin (HPA), which recognises the N-acetyl-D-galactosamine ligand,
N1-methylnicotinamide level in the blood after nicotinamide loading as further evidence for malignant tumor burden.
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Nicotinamide methyltransferase (Nmd CH3transferase) activity increased in the liver of mice after i.p. transplantation of Ehrlich ascites tumor (ascitic form), but not in the liver of mice with acute inflammation induced by the i.p. administration of D-galactosamine, and it rather showed a decrease
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