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diabetes mellitus type 2/protease
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6 risultati
Treatment of insulin resistance and type 2 diabetes mellitus with a thiol protease inhibitor
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FIELD OF THE INVENTION
This invention relates to a pharmaceutical composition and method for the treatment of Type 2 diabetes mellitus and insulin resistance. More particularly, a thiol protease inhibitor is administered to a diabetic patient to reduce insulin resistance.
BACKGROUND OF THE
Stabilized insulinotropic peptides and methods of use
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BACKGROUND
Diabetes refers to a disease process resulting in abnormal glucose homeostasis that is derived from multiple causative factors and characterized by elevated levels of glucose in the blood (i.e., hyperglycemia). Persistent or uncontrolled hyperglycemia is associated with increased and
Stabilized insulinotropic peptides and methods of use
Solo gli utenti registrati possono tradurre articoli
Entra registrati
BACKGROUND
Diabetes refers to a disease process resulting in abnormal glucose homeostasis that is derived from multiple causative factors and characterized by elevated levels of glucose in the blood (i.e., hyperglycemia). Persistent or uncontrolled hyperglycemia is associated with increased and
Stabilized insulinotropic peptides and methods of use
Solo gli utenti registrati possono tradurre articoli
Entra registrati
BACKGROUND
Diabetes refers to a disease process resulting in abnormal glucose homeostasis that is derived from multiple causative factors and characterized by elevated levels of glucose in the blood (i.e., hyperglycemia). Persistent or uncontrolled hyperglycemia is associated with increased and
Inhibitors of dipeptidyl peptidase IV
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The present invention relates to novel compounds that are inhibitors of post-proline aminopeptidases. The compounds are useful as antiproliferative agents and in the treatment of, inter alia, type 2 diabetes and impaired glucose tolerance.
BACKGROUND
The enzyme dipeptidyl peptidase IV, herein
Inhibitors of amyloid formation
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FIELD OF THE INVENTION
This invention concerns pharmaceutical compositions that are useful for inhibiting formation of amyloid deposits in amyloidogenic disorders, such as those deposits associated with protease resistant prion proteins in transmissible spongiform encephalopathies.
BACKGROUND OF THE
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