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diabetes mellitus type 2/triacylglycerol

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15 risultati

Effect of Dietary Oils as G-protein-coupled Receptor Agonists on Glucose Tolerance

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During the last decade, several G protein-coupled receptors (GPCR) that respond to dietary lipid metabolites including free fatty acids (FFAs) have been discovered. These receptors have been implicated in metabolic processes and inflammation. Consequently, several of the receptors have attracted

Plasma Dihydroceramides Are Associated With Hepatic Steatosis in Type 1 and Type 2 Diabetes

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Sphingolipids represent a major class of lipids that are structural and signaling molecules. Major bioactive sphingolipids include ceramide, dihydroceramide, sphingosine, sphingosine-1-phosphate and sphingomyelin. Sphingoliplids are involved in development of various chronic metabolic diseases. Some

Omega 3 and Fibre Intervention Study to Improve Metabolic Health

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Diet and nutrition are key determinants of chronic disease. However, additional information is needed on which bioactive compounds and in what amounts they should be consumed to obtain a given health benefit. One of the biggest recent breakthroughs in science has been realisation of the importance

Very Low Density Lipoprotein Turnover in Young and Elderly Individuals

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Several studies have shown an association between hypertriacylglycerolaemia and coronary artery disease. Additionally, ectopic fat distribution, in particular, deposition of excess lipid within the liver and skeletal muscle, has been shown to correlate negatively with insulin sensitivity, thus

A Nutritional Intervention for Diabetic Neuropathy (WCCR-DN2)

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The following determinations will be made at baseline, mid-point, and end of each 20-week study period, as well as at one-year follow up: General status, symptoms, and medication accounting. Participants will be asked to report changes in their health and medication use. Disease Activity. The

Effects of Triacylglycerol Structure on Gut Hormones and Haemostatic Markers

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Subjects aged between 30 and 60 years old (male and female) with Type 2 diabetes mellitus (T2DM) will be recruited for this study. A randomized, crossover, double-blind study design will be carried out to investigate the acute effects of high fat meals prepared using palm olein (PO), chemically

Effect of Diacylglycerol Oil on Risk Factors of Type 2 Diabetes and Complicating Disease, and Mechanism

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A Nutritional Intervention for Diabetic Neuropathy

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The following determinations will be made at baseline, mid-point, and end of each 20-week study period, as well as at one-year follow up: General status, symptoms, and medication accounting. Participants will be asked to report changes in their health and medication use. Disease Activity. The

Soluble Dietary Fibres in the Prevention of Type 2 Diabetes Mellitus

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This will be a parallel randomized controlled intervention study on free-living adults with diabetes. The study duration will be 6 months. Participants will be randomized to receive one of two dietary approaches (moderate fat, control; and, moderate fat inclusive of 32 g peanuts or 2 Tbsp. peanut

Healthy Fatty Acids in Transition

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Commonly consumed vegetable fats and oils are comprised predominantly of TAG, and small amounts of DAG and monoacylglycerol. TAG consists of 3 fatty acid ester, whereas diacylglycerol oil has 2 fatty acid esters linked to a glycerol backbone. Recently, Watanabe et al., developed a process by which

Development of Biomarker for Development of Non-Alcoholic Steatohepatitis (NASH) in Children

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NASH is a clinico-pathological entity characterized by the development of histological changes of inflammation and fibrosis in the liver that are nearly identical to those induced by excessive alcohol intake, but in the absence of alcohol abuse. Nonalcoholic steatohepatitis occurs commonly children

Postprandial Fatty Acids and FABP2 in Type 2 Diabetes Mellitus (DM)

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Background: The presence of Ala54Thr polymorphism of intestinal fatty acid-binding protein 2 gene (FABP2) might influence the intestinal absorption of dietary fatty acids (FAs) and has been associated with diabetic nephropathy. Objective: We studied the postprandial serum FAs in type 2 diabetic
Atherosclerotic cardiovascular disease remains the leading cause of death in industrialized nations despite major advances in its diagnosis, treatment and prevention. While there has been a trend over the last half century showing a general decline in the age-adjusted death rates of heart disease

Differential Metabolism of Dietary Fatty Acids

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Our Preliminary Data indicate that the rate of oleic acid (OA) oxidation (amount/unit time) is 21% increased compared to palmitic acid (PA) when both fatty acids are fed to the same person at the same intake. We hypothesize that if the ratio of OA to PA in the diet were to increase, the rate of
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