digoxin/carie dentaria

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Influence of kaolin-pectin suspension on steady-state plasma digoxin levels.

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The effect of a kaolin-pectin antidiarrheal mixture on steady-state plasma levels of orally administered digoxin in subjects receiving chronic digoxin therapy was evaluated when the antidiarrheal and the cardiac glycoside were given concomitantly and when two doses of antidiarrheal were given, one 2

Study of insolubility problems of dexamethasone and digoxin: cyclodextrin complexation.

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Cyclodextrins are able to form inclusion complexes with a number of drugs if their molecular dimensions correspond to those of the cyclodextrin cavity which leads to change of physicochemical and biopharmaceutical properties of drugs. 2-Hydroxypropyl beta cyclodextrin (HP beta CD) is suitable for

Effect of Digoxin on Ventricular Remodeling and Responsiveness of beta-Adrenoceptors in Chronic Volume Overload.

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BACKGROUND: Digoxin improves baroreflex function and reduces neurohumoral activation in severe heart failure, but it is uncertain how digoxin affects ventricular remodeling and progression to left ventricular dysfunction. In addition, the effect of digoxin in in vitro beta-adrenoceptor density and

Distribution of lidocaine and digoxin in heart tissues and aorta following intrapericardial administration.

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The distribution of lidocaine and digoxin in myocardial and aorta tissues of open chest anesthetized dogs was studied, following the administration of 30 ml phosphate buffer solution of the drugs in the pericardial cavity where it was kept for increasing time intervals. Transfer of lidocaine (15 or

Fetal uptake of intraamniotic digoxin in sheep.

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To explore the possibility that intraamniotic administration of digoxin is an effective treatment regimen for fetal tachyarrhythmia, we injected digoxin into the amniotic fluid cavity of pregnant sheep and examined the time course of digoxin distribution to the fetal and maternal plasma

Utilization of antidrug antibody fragments for the optimization of intraperitoneal drug therapy: studies using digoxin as a model drug.

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The direct administration of chemotherapeutic agents into the peritoneal cavity has been investigated as a method to treat cancers residing within the peritoneum. The benefits of i.p. drug administration are limited, however, by the systemic toxicity of antineoplastic drugs which diffuse out of the

Digoxin-like immunoreactivity in early infantile death.

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The aim of this study was to determine if the level of digoxin-like immunoreactivity in post-mortem sera obtained from infants differs according to the cause of death and if the level is related to age, post-mortem interval, cardiac pathology or adrenal weight. Twelve infants whose deaths were

Dental caries experience in children with congenital heart disease: a case-control study.

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OBJECTIVE To compare the dental health of a group of children with complex congenital heart disease with that of age and gender matched healthy controls. METHODS Case-control study. METHODS Faculty of Medicine and Odontology/Pediatric cardiology and Pedodontics, Umeå University, Sweden. METHODS All

Water channel AQP-1 in the primary cell culture of rat peritoneum.

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To analyze the regulation of water channels in the peritoneum, we tried to establish a primary mesothelial cell culture system. Male Sprague-Dawley rats weighing about 250 g were anesthetized, and 10 mL of phosphate-buffered saline (PBS) containing 0.25% trypsin and 1 mmol/L ethylenediamine

Congestive heart failure associated with myxomatous degeneration of the left atrioventricular valve in a parakeet.

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Congestive heart failure was diagnosed in a 27-year-old Indian ringneck parakeet with exercise-induced dyspnea. A grade IV/VI holosystolic murmur that radiated to the right sternal area was auscultated over the left side of the sternum. Radiography revealed progressive cardiomegaly, hepatomegaly,

[Evaluation of the hemodynamic effects of the long-acting peripheral vasodilator flosequinan in patients with chronic heart failure].

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The hemodynamic effects of the peripheral vasodilator flosequinan, 100 mg/day, were evaluated in 20 patients with Stage IIA-IIB (the Lang-Strazhesko-Vasilenko classification) heart failure. The doses of digoxin and diuretics were found to be stable. The right cardiac cavities and pulmonary artery

Congestive heart failure in hypertensive patients with normal systolic function and dynamic left ventricular outflow obstruction.

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BACKGROUND Hypertensive patients with left ventricular hypertrophy and normal systolic function can develop congestive heart failure refractory to conventional drug therapy with digoxin, diuretic, and vasodilators. METHODS We studied 8 patients with a history of systemic hypertension (6 females and

Effect of gender and left ventricular dysfunction on the incidence of hypotension induced by dobutamine stress echocardiography.

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BACKGROUND Of patients who undergo dobutamine stress echocardiography (DSE), 14% to 38% experience hypotension that sometimes requires termination of the test before an adequate cardiac work-load is reached. The mechanisms of hypotension reportedly are related to peripheral vasodilation, a decrease

Nasal nitric oxide concentration is decreased in heart failure patients receiving nitrates.

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Nitric oxide (NO) is a free radical gas and a short-lived messenger which has many paracrine functions. Direct assessment of NO production is very difficult in vivo. However, the paranasal cavities generate a high amount of NO which diffuses in the nasal cavity where it can be easily measured.

Molecular modeling of cardiac glycoside binding by the human sequence monoclonal antibody 1B3.

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The amino acid sequences of the heavy- and light-chain variable regions of the high-affinity human sequence antidigoxin monoclonal antibody 1B3 (mAb 1B3) were determined, and a structural model for the mAb's variable region was developed by homology modeling techniques. The structural model provided

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