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Pagina 1 a partire dal 35 risultati
Effect of CO2, calcium, digoxin, and potassium on cardiac and skeletal muscle metabolism in malignant hyperthermia susceptible swine.
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The effects on whole body or cardiac metabolism of carbon dioxide, calcium, potassium, or digoxin were studied in 16 normal swine and 31 swine susceptible to malignant hyperthermia (MHS). Malignant hyperthermia (MH) was defined as an increase in metabolism that occurred in MHS but not in normal
Digoxin-like immunoreactivity detected in cerebrospinal fluid of humans with fever.
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A diminished response to digoxin in isolated heart muscle as a result of fever.
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[Effect of temperature on the kinetics of propranolol, theophylline, phenytoin and digoxin in rats (author's transl)].
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1. The effect of chronic hyperthermia (35 degree C for 1 month) on the kinetics of propranolol, theophylline, diphenylhydantoin and digoxin was studied in groups of male Wistar rats. 2. Each compound was administered by intravenous injection, dosage being 2 mg/kg for propranolol, 3 mg/kg for
Toxicity of digoxin in acutely and chronically heat-exposed rats.
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Rats exposed acutely or chronically to high ambient temperatures (35 degrees C) were much more susceptible to digoxin toxicity than rats kept at 22 degrees C. LD 50 values were 8.8 +/- 1.8 mg/kg in the acute group and 10 +/- 5 2.5 mg/kg in the chronic group, which contrasted with 32.0 +/- 4.4 mg/kg
[Significance of serum digoxin concentration and its influencing factors].
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In recent years it has become possible by means of a radioimmunoassay to measure Digoxin concentration in the serum of digitalized patients. With this method it could be shown that the resorption of Digoxin is decreased by partial resection of the samll intestines, by malabsorption syndromes, after
[Q-fever as a cause of myocarditis in childhood].
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Q-fever occurs in The Netherlands in childhood more often than used to be believed. We treated an 8-month-old infant with congestive myocarditis associated with a seroconversion against Coxiella burnetii. The infection was probably caused by the father, who a few weeks earlier had visited his native
Pharmacokinetics of digoxin in children with congestive heart failure aggravated by other diseases.
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OBJECTIVE
To determine individual digoxin level variations and the effect of some common diseases those aggravate congestive heart failure (CHF) on digoxin pharmacokinetics in children.
METHODS
Digoxin pharmacokinetics was evaluated in 11 children with CHF and an additional disease, such as
Pharmacokinetics and efficacy of digoxin specific Fab fragments in a child following massive digoxin overdose.
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The use of digoxin-specific Fab fragments (d-Fab) to treat life-threatening digitalis intoxication has been widely substantiated in adults. This reports a case of a 2-year-old girl who ingested 90-92, 0.25 mg tablets of digoxin and within four hours, developed vomiting, lethargy, tachycardia and AV
Case files of the medical toxicology fellowship of the California poison control system-San Francisco: calcium plus digoxin-more taboo than toxic?
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A 68 year old woman with a history of diabetes mellitus presented to the emergency department after experiencing several days of nausea and vomiting. Recorded vital signs included: blood pressure 98/32 mm Hg, heart rate 69 bpm, "normal" respirations, and no fever. Her initial ECG revealed peaked T
Treatment of heart failure with normal ejection fraction.
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UNASSIGNED
Heart failure (HF) is a major cause of mortality and morbidity and one of the most frequent reasons for hospital admission in the United States and Europe. Currently, more than 50% of HF patients have a normal (N) left ventricular (LV) ejection fraction (EF) (LVEF >50%). The main
Imported Plasmodium vivax malaria complicated by reversible myocarditis.
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Myocarditis as a result of malaria infection is uncommon. However, we report a case of a Pakistani emigrant who presented with respiratory distress, fever, chills, and nausea at the emergency room. The patient had traveled to visit his relatives in Pakistan without receiving antimalarial
Anaesthetic implications of calcium channel blockers.
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Clinical uses of calcium channel blockers are expanding. In addition to the established uses in patients with arrhythmias, angina pectoris or hypertension, newer and to some extent investigational uses indicate widespread application. For instance, their use has been reported in hypertrophic
[Two cases of Candida endocarditis associated with abdominal disease].
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Two cases of Candida endocarditis are reported. The first case was of a 63-year-old man who had a positive blood culture for Candida albicans during treatment for liver abscess and early gastric cancer. He was transferred to our department, and aortic and tricuspid regurgitation due to Candida
Quinidine-induced hepatotoxicity revisited.
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Although quinidine has been widely used since the beginning of the century, quinidine-induced hepatotoxicity has been recently reported in the literature. We describe a reversible case of quinidine-induced hepatotoxicity. A 62-y-old male with a past medical history of atrial flutter and adult onset
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