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Pagina 1 a partire dal 16 risultati
Evaluation of the Effect of tDCS on Cannabis Craving
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Effects of Cannabis on Cognition and Endocannabinoid Levels in Bipolar Disorder Patients and Healthy Volunteers
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Effect of AEF0117 on Subjective Effects of Cannabis in CUD Subjects
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Cannabis use is increasing and will only further escalate with legalization of recreational and medical cannabis use in western countries , with a prevalence greater than 30 % in the US and most European countries for individuals between 16 and 24 years of age. Approximately 9 % of those who use
Lorcaserin for Cannabis Use Disorder
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Cannabis use disorder (CUD) is a major public health problem associated with significant psychiatric and medical morbidity, poor performance, and legal consequences.4 4.2 million people in the United States meet criteria for CUD.5 15% of all admissions for substance abuse treatment were related to
The Correlation of Women's Sexual Health and Marijuana Use
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Marijuana is the most commonly used illicit drug (19.8 million past-month users) according to the 2013 National Survey on Drug Use and Health (NSDUH).
There is a current movement towards the legalization of marijuana in various states and there are numerous claims of potential uses in medicine.
The
Buspirone, Stress, and Attentional Bias to Marijuana Cues
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For nearly 40 years marijuana has remained the most widely used illicit drug in the US, with more than 50% of first-time users < age 18. Marijuana accounts for ≈ 60% of illicit substance use disorders (SUD) in the US, bearing by percent the largest US public health burden among illicit substances.
Quetiapine Pharmacotherapy for Cannabis Dependence
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In a 12-week randomized double-blind placebo-controlled clinical trial, we will evaluate the efficacy of quetiapine for the treatment of marijuana dependence in 150 outpatients. Participants will be randomly assigned to treatment under double-blind conditions with either a fixed dosing schedule of
The Pharmaco-genetic and Brain Mechanisms Associated With Cannabis- Induced Psychosis
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Genetic association study will be performed in 100 young cannabis users (age 18-26 years) for genes that are related to the neurotransmitters dopamine (D2, DAT, COMT), GABA, glutamate and the cannabinoid receptor CB1. Out of this cohort, 24 male subjects without history of cannabis or drug-induced
Evaluation of the Effects of Treatment of Psycho-stimulant and Cannabis-dependent Users in Israel
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There is a significant number of cannabis and psychostimulant users that experience psychotic episodes and require psychiatric treatment. This study evaluates the effects of psychological and pharmacological treatment of regular users of cannabis and psychostimulants in a treatment center (Kfar
Clinical Trial of N-acetylcysteine Versus Placebo Efficacy in the Cannabis Withdrawal
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Introduction:There are few clinical trials on pharmacotherapies in marijuana dependence. There is no randomized and double-blind trial on N-acetylcysteine efficacy in marijuana withdrawal.Aims:The first aim is to assess the efficacy in human (n=150 outpatients) of N-acetylcysteine versus placebo
Imaging Cannabinoid CB1 Receptors in Schizophrenia
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Schizophrenia is a debilitating mental disorder with a complex and multifactorial etiology. The exact pathophysiological mechanisms have remained elusive, but a large body of evidence points toward abnormalities in a number of brain neurotransmitter systems: dopamine, glutamate, and gamma-amino
Study of Quetiapine Treatment for Cannabis Dependence
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Conceptually, the pharmacodynamic and clinical actions of quetiapine suggest that it may be useful for cannabis dependence. By antagonizing dopamine, quetiapine may interfere with the reinforcing effects of cannabis, while serotonin type 2A, histamine type 1, and adrenergic receptor antagonism may
Cannabis and Schizophrenia: Self-Medication and Agonist Treatment
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Cannabis use disorder (CUD) is up to ten times more common in schizophrenia (SCZ) than in the general population, and substantially worsens the course of this severe psychiatric disorder. Since SCZ occurs in 1% of the population, the comorbidity of CUD in 13% to 42% of people with this disorder
Imaging Cannabinoid CB1 Receptors in Alcohol Dependence
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Alcohol dependence (alcoholism) is a chronic medical illness with a relapsing course and a major public health problem. Alcoholism is clinically characterized by periods of uncontrolled alcohol consumption and withdrawal, during which counter-adaptive mechanisms such as stress and dysphoria are
First Episode Schizophrenia and Cannabis-Related Disorder Study
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Schizophrenia is a relapsing disorder that produces profound effects on those afflicted once it becomes chronic, often leading to a severe and long-term disability. However, during the initial years of illness many patients are more treatment responsive and may achieve substantial periods of
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