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dopamine/nausea

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D4 receptor selectivity piperazine derivatives

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The invention relates to piperazine derivatives of the formula I ##STR2## in which R.sup.1 is pyridyl or phenyl, each of which is monosubstituted by Ph or by 2- or 3-thienyl, R.sup.2 is Ph' or Het, Ph and Ph' in each case independently of one another are phenyl, it being possible for both radicals

Tetrahydropyridinyldibenzazepine derivatives

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The invention relates to tetrahydropyridinyldibenzazepine derivatives of formula I ##STR2## wherein R.sub.1 is a substituent selected from the group consisting of hydrogen, halogen, and lower alkyl; R.sub.2 is selected from hydrogen, and unsubstituted or hydroxy substituted lower alkyl or lower

Aromatic amides of heterocyclic compounds and therapeutic compositions containing same

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SUMMARY OF THE INVENTION According to our invention, in its broadest aspect, we provide a compound corresponding to the general formula (I): ##STR1## in which: R is a lower (C.sub.1 -C.sub.6) alkoxy or alkenoxy; R.sub.1 and R.sub.2, which may be the same or different, are selected from hydrogen,

Anti-emetic esters of cyproheptadine-3-carboxylic acid and structurally related compounds

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BACKGROUND OF THE INVENTION This invention is concerned with compounds of structural formula I: ##STR1## wherein X is --CH.dbd.CH--, --CH.sub.2 --CH.sub.2 --, --CH.sub.2 --O--, --O--CH.sub.2 --, --S--CH.sub.2 --, --CH.sub.2 --S--, --S-- or --O--, and R is a 5- or 6-membered nitrogen heterocyclic

Anti-emetic esters of cyproheptadine-3-carboxylic acid and structurally related compounds

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BACKGROUND OF THE INVENTION This invention is concerned with compounds of structural formula I: ##STR1## wherein X is --CH.dbd.CH--, --CH.sub.2 --CH.sub.2 --, --CH.sub.2 --O--, --O--CH.sub.2 --, --S--CH.sub.2 --, --CH.sub.2 --S--, --S-- or --O--, and R is a 5- or 6-membered nitrogen heterocyclic

Anti-psychotic (cycloalkenylalkylpiperidino) benzamides

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SUMMARY OF THE INVENTION According to one aspect of our invention, we provide compounds of the general formula ##STR1## wherein R represents a lower alkoxy or lower alkenyloxy group; R.sup.1 and R.sup.2, which may be the same or different, each represent a hydrogen or halogen atom, or a
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