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gluten/atrofia

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Coeliac disease (CD) is an autoimmune condition by the exposure to gluten in patients who are genetically susceptible. The global prevalence is thought to be 1%, and incidence rate of CD in the UK is approximately 13.8 per 100,000 person-years with greater than fourfold increase in incidence over

Intestinal Permeability, Nutritional Status and Quality of Life in Celiac Disease

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Celiac disease is defined as an autoimmune enteropathy that progresses with malabsorption of gluten protein found in wheat, barley, rye and small intestinal mucosal inflammation in individuals with genetic predisposition. Disruption of intestinal barrier integrity play role in the pathogenesis of

Anti-Tissue Transglutaminase IgA Antibodies

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Within this definition, patients can further be defined as having silent, potential, or latent celiac disease. The term silent celiac disease refers to patients fulfilling the definition above, but presenting no symptoms. Typically, such diagnoses are made by screening asymptomatic individuals, who

Effectiveness of PENTABIOCEL in Clinical and Laboratory Recovery of Children With Celiac Disease

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Celiac disease (CD) is an intestinal inflammatory condition characterized by permanent intolerance to gluten, a protein complex present in wheat, barley, and rye, in genetically predisposed subjects. In the early phase of the disease, specific autoantibodies are generally present, which is relevant

"Gluten Friendly" Treatment in Celiac Disease

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Background: Gluten ingestion leads to small intestinal mucosal injury in patients with celiac disease (CD), necessitating rigid, life-long exclusion of gluten from diet. Current therapies based on gluten-free dietary regimes, are also impairing social life, increased expenses for gluten free

Comparison Between Axial- and Lateral-viewing Capsule Endoscopy in Celiac Disease

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The study will involve 25 patients with suspected complicated celiac disease , which for clinical reasons are referred for an evaluation of the small intestine by means of capsule endoscopic in order to screen/identify complications. Furthermore, patients under regular follow-up for a known

Pre-endoscopy Serological Testing for Coeliac Disease; a Novel Approach Using Rapid Antibody Testing

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Coeliac disease is the most common chronic inflammatory bowel condition encountered by physicians. Internationally the prevalence estimated by serological screening in healthy volunteers is between 0.5-1.0%. Historically, patients with adult coeliac disease complained of symptoms suggestive of

Non-Celiac Wheat Sensitivity: Permanent or Transient Condition?

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Non-Celiac Gluten Sensitivity (NCGS) has been recently included among the gluten-related diseases. Patients suffering from NCGS are diagnosed after carefully excluding celiac disease (CD) diagnosis by negative CD-specific serum antibodies and absence of intestinal villi atrophy, and excluding

Lymphocytic Enteritis and Suspected Coeliac Disease: Gluten vs Placebo

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Duodenal intraepithelial lymphocytosis (lymphocytic enteritis, LE) is defined by normal villous architecture and intraepithelial lymphocytes (IEL) >25/100 enterocytes. It is a frequent finding present in 2% to 5,4% of duodenal biopsies. LE is secondary to coeliac disease (CoD) in only a minority of

Celiac Disease and Infertility Among Men and Women in Denmark

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Aims of the study: - To investigate the prevalence of CD in a cohort of men and women referred to fertility treatment in Danish fertility clinics - To compare individuals diagnosed with CD to individuals without the disease to investigate: - possible predictive symptoms of CD (fertility history,

Noninvasive Markers of Gluten Ingestion in Celiac Disease Patients

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The gold-standard for monitoring of dietary adherence is consultation with an expert dietitian, but this may be time-consuming for patients and local expertise may not be available. Intestinal biopsy is the only direct method to document mucosal healing and can be considered in all adults with
Celiac disease (CD) is a chronic immune-mediated disorder that occurs in genetically predisposed populations. Patients affected by the disease may be asymptomatic or manifest classic malabsorption symptoms of diarrhea, steatorrhea, abdominal pain, and weight loss after gluten ingestion (and related

Antibody Treatment for Advanced Celiac Disease

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Background: - Celiac disease is a complex inflammatory disorder with an autoimmune component characterized by a dramatic expansion of intraepithelial cytotoxic T lymphocytes that usually regress on a gluten-free diet. - It is estimated that approximately 10% of patients become refractory on a

Infant Nutrition and Risk of Celiac Disease

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From weaning to age 12 months the clinical data, the adherence to the dietary protocol and the amount of intervention baby-food ingested will be checked every month. Following investigations will be performed at the time of recruitment, at time of weaning and at 12, 18, 24, 30,36, 42, 48, 54 and 60

Gluten-free Diet in Gluten-genetically Predisposed Subjects

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Celiac disease (CD) is an autoimmune enteropathy triggered by ingestion of gluten in genetically susceptible subjects and is one of the most frequently occurring, treatable, lifelong disorders. In this disease we recognize the trigger (gluten), the genetic factor (HLA DQ2/8), the auto-antigen (the
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