6 risultati
CROSS-REFERENCE TO RELATED APPLICATION
This application claims priority to and is a 35 U.S.C. .sctn. 371 national phase application of PCT/KR2015/001889 (WO2015/130109), filed on Feb. 26, 2015 entitled "Pharmaceutical Composition for Cancer Treatment Containing Gossypol and Phenformin as Active
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention is related to the use of gossypol acetic acid as an anti-tumor agent effective against human cancers susceptible thereto.
2. Description of the Related Art
Gossypol is a double biphenolic compound derived from crude
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention is related to the use of gossypol and related compounds as anti-tumor agents effective against human cancers including, but not limited to, adrenocortical carcinoma, uterine, cervical, ovarian and testicular carcinoma,
A subject of the present invention is gossypol derivatives, and more particularly reduced and oxidized derivatives of gossypolone, as well as the methods for obtaining them and their uses, in particular in pharmaceutical compositions intended for the treatment of cancers.
Gossypol is generally
FIELD OF THE INVENTION
The present invention relates to naturally occurring and chemically synthesized small molecule antagonists of Bcl-2 family proteins. In particular, the present invention provides gossypol compounds (e.g., isomers, enantiomers, racemic compounds, metabolites, derivatives,
FIELD OF THE INVENTION
The present invention relates to naturally occurring and chemically synthesized small molecule antagonists of Bcl-2 family proteins. In particular, the present invention provides gossypol compounds (e.g., isomers, enantiomers, racemic compounds, metabolites, derivatives,