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hepatitis d/tyrosine
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4 risultati
Generation of cytotoxicity against hepatitis delta virus genotypes and quasispecies by epitope modification.
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OBJECTIVE
Quasispecies are likely responsible for virus escape from host immune surveillance. The aim of this study was to enhance the immune response against varied sequences within the HDV quasispecies in an attempt to control chronic delta hepatitis.
METHODS
The HLA-A2 restricted peptides
A screening assay for the identification of host cell requirements and antiviral targets for hepatitis D virus infection.
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Hepatitis delta virus (HDV) is a minimalistic satellite virus of hepatitis B virus (HBV). HBV/HDV co-infection, i.e. "hepatitis D", is the most severe form of viral hepatitis. No effective therapy for HDV infection is available partly due to the fact that HDV is a highly host-dependent virus devoid
Hepatitis delta virus inhibits alpha interferon signaling.
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Hepatitis delta virus (HDV) can cause severe acute and chronic liver disease in patients infected with hepatitis B virus. Interferon-alpha (IFN-alpha) is the only treatment reported to be effective in chronic hepatitis delta, albeit in a minority of patients. The molecular mechanisms underlying
Clade homogeneity and low rate of delta virus despite hyperendemicity of hepatitis B virus in Ethiopia.
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Although hepatitis B virus (HBV) is hyperendemic and heterogeneous in its genetic diversity in Ethiopia, little is known about hepatitis D virus (HDV) circulating genotypes and molecular diversity.
A total of 321 hepatitis B surface antigen (HBsAg) positives (125 HIV co-infected, 102 liver disease
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