hypospadias/astenia

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Myopathy with abnormal distribution of dystrophin, growth retardation, mental retardation, and hypospadia.

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A 9-year-old boy with severe growth retardation, mild mental retardation, and hypospadia had a high serum CK level without muscle weakness and atrophy. Muscle biopsy revealed a moderate variation in fiber size with a few necrotic and scattered regenerating fibers. Although muscle membranes were

Proximal hypospadias repair using the koyanagi-hayashi technique. A review of 15 cases

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Background: Several surgical approaches or modifications of existing techniques have been described for the repair of hypospadias. In Sub-Saharan Africa, a two-stage approach is the preferred option in proximal cases with severe penile

Ultrasound-Guided Pudendal Block is a Viable Alternative to Caudal Block for Hypospadias Surgery: a Single Surgeon Pilot Study.

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OBJECTIVE To evaluate pudendal nerve block as an alternative to caudal block for hypospadias surgery. METHODS Data were obtained by chart review. Children who underwent hypospadias repair between 2012 and 2016 by a single surgeon at an academic institution were included. Patients received

Analgesic efficacy and impact of caudal block on surgical complications of hypospadias repair: a systematic review and meta-analysis.

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is commonly used for children undergoing hypospadias repair. However, the safety of caudal block for hypospadias repair in children is controversial in terms of surgical complications such as urethrocutaneous fistula and glans dehiscence. We sought to perform a meta-analysis to

Multiple Acyl-CoA Dehydrogenase Deficiency

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Clinical characteristics: Multiple acyl-CoA dehydrogenase deficiency (MADD) represents a clinical spectrum in which presentations can be divided into type I (neonatal onset with congenital anomalies), type II (neonatal onset without

Hypogonadism and fertility issues following primary treatment for testicular cancer.

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BACKGROUND The majority of testicular cancer (TC) patients are cured and expected to live for decades after treatment, such that knowledge about hypogonadism and fertility issues is particularly important for the group of testicular cancer survivors (TCSs). Hypogonadism and fertility issues are

Onset Manifestations of Spinal and Bulbar Muscular Atrophy (Kennedy's Disease).

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Spinal and bulbar muscular atrophy (SBMA) is regarded as a disorder with adult onset between third and fifth decade of life. However, there is increasing evidence that SBMA may start already before adulthood. The present study investigated the following: (1) Which clinical manifestations have been

Severe dystrophinopathy in a patient with congenital hypotonia.

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We studied a 2-year-old child with congenital hypotonia and proximal muscle weakness. There was no family history of neuromuscular disease. The child also had hypospadia. The central nervous system was apparently not involved. Muscle biopsy showed a dystrophic pattern and dystrophin was absent as

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