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jimsonweed/edema

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In field observations of young cattle grazing on certain high-altitude ranges infested with the locoweed Oxytropis sericea, a high frequency of clinical congestive right ventricular failure was identified. At necropsy of affected calves, there were right ventricular hypertrophy and dilation,

Neurologic disease in range goats associated with Oxytropis sericea (Locoweed) poisoning and water deprivation.

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About 200/2500 Spanish goats foraging on mountain rangelands of western Montana developed neurologic disease with severe rear limb weakness, knuckling of the rear fetlocks, and a hopping gait. Sick goats were of all ages and in good flesh, though they often had dull, shaggy coats. Some mildly
Ultrasonographic imaging was used to monitor the effects of locoweed (Astragalus lentiginosus) on fetal, placental, and cotyledonary developments in pregnant ewes and proved to be a useful noninvasive method of monitoring the effects of locoweed poisoning on fetal and placental development.

Effect of locoweed (Astragalus ientiginosus) feeding of fetal lamb development.

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Locoweed, Astragalus lentiginosus, was fed to pregnant ewes for various periods during gestation. The principal gross effects on the developing fetuses were observed to be delayed placentation, decreased vascularization, fetal edema and hemorrhage, and alteration of cotyledon development. Deformed

Locoweeds: effects on reproduction in livestock.

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Locoweeds (species of Oxytropis and Astragalus containing the toxin swainsonine) cause severe adverse effects on reproductive function in livestock. All aspects of reproduction can be affected: mating behavior and libido in males; estrus in females; abortion/embryonic loss of the fetus; and

Swainsonine-induced high mountain disease in calves.

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Swainsonine, an indolizidine alkaloid in the locoweeds (certain species of the Astragalus and Oxytropis genera), was fed to young Holstein bull calves in their milk at high elevation (3090 m), and the incidence of high mountain disease (HMD) was compared with locoweed-fed and control calves. Five of

Cattle grazing Wahweap milkvetch in southeastern Utah.

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Cattle's grazing of the locoweed Wahweap milkvetch (Astragalus lentiginosus var. wahweapensis) was evaluated on desert and foothill winter range during the winter of 1986 to 1987. Dry, dead stalks of Wahweap milkvetch that had grown in 1985 and 1986 made up 15% of cattle diets overall, and 24% of
Ingestion of locoweed (Astragalus spp. and Oxytropis spp.) by pregnant livestock may result in fetal malformations, delayed placentation, reduced placental and uterine vascular development, hydrops amnii, hydrops allantois, abnormal cotyledonary development, interruption of fetal fluid balance, and
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