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Pagina 1 a partire dal 187 risultati
The evaluation of mannitol therapy in acute ischemic stroke patients by serial somatosensory evoked potentials.
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The effects of mannitol infusion therapy on acute ischemic stroke were investigated by serial median nerve somatosensory evoked potentials (SEP) in 31 patients with abnormal SEP recordings within 72 hours after onset. In 10 patients with missing N20 waves mannitol had no effect. In 12 patients
Mannitol use in acute stroke: case fatality at 30 days and 1 year.
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OBJECTIVE
Mannitol is used worldwide to treat acute stroke, although its efficacy and safety have not been proven by randomized trials.
METHODS
In a tricenter, prospective study, we analyzed the 30-day and 1-year case fatality with respect to mannitol treatment status in 805 patients consecutively
Mannitol Augments the Effects of Systemical Stem Cell Transplantation without Increasing Cell Migration in a Stroke Animal Model
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Background: Mannitol increases blood-brain barrier permeability and can improve the efficiency of systemically administered stem cells by facilitating stem cell entry from the periphery into the injured brain. The aim of this study was to
Treatment with Mannitol is Associated with Increased Risk for In-Hospital Mortality in Patients with Acute Ischemic Stroke and Cerebral Edema.
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BACKGROUND
Current guidelines state that osmotic therapy is reasonable in patients with clinical deterioration from cerebral infarction-related cerebral edema. However, there are limited data on the safety and efficacy of this therapy. We aimed to evaluate the effect of mannitol on the outcome of
High Stroke Volume Variation Method by Mannitol Administration Can Decrease Blood Loss During Donor Hepatectomy.
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Optimal fluid management to reduce blood loss during donor hepatectomy is important for maximizing donor safety. Mannitol can induce osmotic diuresis, helping prevent increased intravascular volume status. We therefore evaluated the effect of high stroke volume variation (SVV) method by mannitol
Increases in lung and brain water following experimental stroke: effect of mannitol and hypertonic saline.
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OBJECTIVE
Pulmonary edema is a serious condition following brain injury of diverse etiologies, including large hemispheric infarctions. We have previously shown that treatment with hypertonic saline attenuates cerebral edema associated with experimental ischemic stroke. In a well-characterized
[Effect of glycerol, mannitol, and lasix on cerebrospinal fluid pressure in the acute period of a stroke].
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On giving a dose of glycerol (orally), mannitol or lasix (intravenously) to patients with a cerebral stroke in the acute period the cerebrospinal fluid (CSF) pressure in them dropped, on the average, by 70-80%, 65-70%, and 25-30%, respectively. However in 6.5 to 7.5 hours it rose again and the
[Plasma levels of atrial natriuretic factor (ANF) in the stroke patients after glycerol and mannitol infusion].
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This study included 43 patients with stroke in a range of 48 to 85 years of age. Among them, 24 were male and 19 were female. Changes in blood pressure, plasma ANF (by radioimmunoassay), serum sodium, and serum osmolarity before and 40 minutes after hyperosmotic agents infusion were studied. The
Transcranial doppler monitoring of intracranial pressure therapy with mannitol, sorbitol and glycerol in patients with acute stroke.
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BACKGROUND
The noninvasive management of the conservative therapy for intracranial pressure (ICP) with hyperosmolar substances is a central problem in the treatment of brain edema. Using transcranial Doppler (TCD), a continuous monitoring of ICP is now possible, because the TCD pulsatility index
Mannitol for acute stroke.
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BACKGROUND
Mannitol is an osmotic agent and a free radical scavenger so it might decrease oedema and tissue damage in stroke.
OBJECTIVE
To test whether treatment with mannitol reduces short and long-term case fatality and dependency after acute ischaemic stroke or cerebral parenchymal
The puzzle of neuronal death and life: is mannitol the right drug for the treatment of brain oedema associated with ischaemic stroke?
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Brain oedema is a major factor contributing to the poor outcome of subjects with acute ischaemic stroke but the use of mannitol and other hyperosmolar agents in this setting is controversial and hardly debated. Recent data have demonstrated that mannitol at concentrations which may be achieved in
Effects of combination treatment with dexamethasone and mannitol on neuronal damage and survival in experimental heat stroke.
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There is evidence that increased plasma cytokines, elevated brain levels of monoamines and hydroxyl radical production may be implicated in pathogenesis during heat stroke in rats. Acute treatment with a combined therapeutic approach has been repeatedly advocated in cerebral ischemia experiments.
Incidence and Risk Factors for Acute Kidney Injury Following Mannitol Infusion in Patients With Acute Stroke: A Retrospective Cohort Study.
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Mannitol, an osmotic diuretic, is commonly used to treat patients with acute brain edema, but its use also increases the risk of developing acute kidney injury (AKI). In this study, we investigated the incidence and risk factors of mannitol-related AKI in acute stroke patients.A total of 432
[Changes of early renal function before and after using mannitol in patients with cerebral apoplexy].
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The alteration of renal function after initiation of mannitol infusion were monitored in 20 patients with cerebrovascular accident to evaluate whether mannitol has nephrotoxicity effects. Serum creatinine and urea nitrogen were increased after initiation of mannitol infusion, but hadn't reached
Effects of intravenous mannitol on EEG recordings in stroke patients.
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OBJECTIVE
To evaluate the usefulness of continuous EEG monitoring of stroke patients during and after intravenously infused mannitol.
METHODS
Patients were rapidly administered 50 g of intravenous mannitol solution with continuous EEG monitoring for 3h pre- and post-drug infusion in the neurological
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