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mannitol/infiammazione

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Pagina 1 a partire dal 65 risultati

Gut Microbiome of Patients Undergoing Antibiotic Therapy for Orthopedic Device-related Infection

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Standardising Nasal Allergen Challenge in Adult With Hay Fever

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Nasal allergen challenge (NAC) is a useful tool in the investigation of allergic rhinitis, including grass pollen-induced seasonal allergic rhinitis (hay fever). We have experience in using NAC to investigate the clinical and immunological effects of allergen exposure and in using NAC as a surrogate

Prebiotics and Diet to Reduce "Leaky" Gut in First Degree Relatives of Crohn's Disease Patients

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1. Background: Crohn's disease (CD) is a chronic intestinal inflammation, affecting approximately 130,000 Canadians. Its incidence and prevalence is rising worldwide. The disease etiology is unknown; however its pathogenesis is thought to be mediated by commensal gut bacteria, affected by

Beta-Hydroxy-Beta-Methylbutyrate Supplementation and Physical Activity in Liver Cirrhosis: a Controlled Trial

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1. Introduction Changes in nutritional status are a frequent complication in cirrhotic patients. The prevalence of malnutrition is related to the severity of the disease and has been reported by 65-90% in advanced cirrhosis. The most significant component of malnutrition is a progressive and

Co-ultra PEALut Enhances Neuronal Recovery Following Moderate Traumatic Brain Injury

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Study Setting All patients affected by moderate TBI (Glasgow Coma Score 9-13) admitted to the neurosurgical department of the University Hospital of Messina, Italy, will be screened for recruitment. Ethics The institutional review board (IRB) approved the study. Written consent will be obtained from
The investigators have previously investigated fertility in patients with asthma (Lundbeck 2011-9502), and found increased time to pregnancy (TTP) in women with asthma compared with non-asthmatic women (55 vs 33 months, p<0.001) and women with asthma had fewer successful pregnancies during fertility

Vascular Implications of a Naturally Occurring Asthma Exacerbation

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BACKGROUND & SCOPE: While asthma is generally considered to be a disease of the airways, there are important systemic consequences which have predisposed people with asthma to become more likely to die from cardiovascular (CV) disease compared to non-asthmatics. Additional CV risks have been

Diagnosis of EIB in Young Elite Athletes (13-18 y)

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State of the art Physical exercise, though absolutely beneficial for human well-being, is a well-known trigger to induce bronchoconstriction. Aretaeus of Cappadocia described the first cases of asthma triggered by exercise, already in the second century AD. Exercise can provoke bronchoconstriction

The Effect of Deep Inhalation on Mannitol Responsiveness

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This study will look at airway responsiveness to inhaled methacholine and mannitol administered with and without deep inhalation. This study will also investigate the role of airway inflammation on these responses, using sputum differential cell counts and fractional exhaled nitric oxide. This is a

Evaluation of the Performance of Two Neutral Oral Contrast Agents in CT Enterography

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Anti-PD 1 Brain Collaboration + Radiotherapy Extension (ABC-X Study)

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1. BACKGROUND The ABC study (NCT02374242) is a phase II clinical trial recruiting 3 cohorts of patients with melanoma brain metastases. 76 patients received immunotherapy with either nivolumab alone or nivolumab combined with ipilimumab. Nivolumab together with ipilimumab was shown to be more

In Vivo Effects of the Gluten Friendly Bread in Coeliac Disease

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The aim of this study is to investigate the effects of gluten friendly bread on the faecal microbiota composition, metabolism and immunity in coeliac individuals aged 20-80 years. The study consists of a 6-visit (screening visit + 5 visits) randomised intervention with the Gluten Friendly bread at

Clinical Features and Histologic Findings in Bladder Pain Syndrome/Interstitial Cystitis

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Between 2005 and 2016, in our Department 57 consecutive patients underwent cystoscopy under anaesthesia to classify those cases suspected of BPS/IC. Patients reported long-lasting irritative bladder symptoms, including urgency, daytime frequency of seven or more episodes, nocturia, and pain in the

The RECONSTRUCT Study - Reconstructing Disease Mechanisms in Asthma

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Purpose and background Inhaled corticosteroids and asthma phenotypes Inhaled corticosteroid (ICS) is a cornerstone in the treatment of asthma. ICS acts locally in the airways through several pathways to limit inflammation, primarily through reduction of eosinophilic inflammation. In clinical

Comparison of VoLumen and Breeza Oral Contrast Agents in Pediatric Patients

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VoLumen, a low Hounsfield unit 0.1% barium sulfate suspension that also contains sorbitol and a gum, is the most common oral contrast material used in children and adults undergoing CT and MR enterography (advanced imaging tests used to evaluate the bowel lumen and bowel wall in children and adults,
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