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methoxsalen/atrofia

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Methoxsalen-induced advanced bull's eye maculopathy.

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A number of systemic medications are known to cause macular toxicity, and bull's eye maculopathy is caused by some of them like hydroxychloroquine and clofazimine. A 55-year-old female, known case of vitiligo with history of undergoing methoxsalen-ultraviolet A therapy, presented with painless

Actinic degeneration in association with long-term use of PUVA.

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To determine the extent of clinical actinic damage that occurred in association with exposure to oral methoxsalen photochemotherapy (PUVA), dermatologists at 16 university centers assessed the wrinkling, telangiectasia, and altered skin markings on the buttocks and the dorsa of the hands among 1380

Treatment of rheumatoid arthritis by extracorporeal photochemotherapy. A pilot study.

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In a 6-month pilot study of 7 patients with rheumatoid arthritis, we tested a treatment involving the extracorporeal photoactivation of biologically inert methoxsalen (8-methoxypsoralen) by ultraviolet A energy to a form that covalently cross-links lymphocyte DNA; the injured cells are reinfused

Photopheresis for rheumatoid arthritis.

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For rheumatoid arthritis, an effective therapy with minimal toxicity would be welcome. In a six-month pilot study of seven patients with a variety of presentations and previous treatments, we tested a therapy involving the extracorporeal photoactivation of biologically inert methoxsalen

Toxicology and Carcinogenesis Studies of 8-Methoxypsoralen (CAS No. 298-81-7) in F344/N Rats (Gavage Studies).

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Oral administration of 8-methoxypsoralen followed by exposure to longwave ultraviolet light (primarily ultraviolet A, 320-400 nm) is used in the treatment of vitiligo and psoriasis. 8-Methoxypsoralen also occurs naturally in a variety of vegetables. Toxicology and carcinogenesis studies of
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