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Endogenous Labile Iron Pool-Mediated Free Radical Generation for Cancer Chemodynamic Therapy

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Current chemodynamic therapy (CDT) primarily relies on the delivery of transition metal ions with Fenton activity to trigger hydroxyl radical production from hydrogen peroxide. However, administration of excess amount of exogenous Fenton-type heavy metals may cause potential adverse effects to human

Chain-Breaking Antioxidant Capability of Some Beverages as Determined by the Clark Electrode Technique.

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The protective effects of red wine, tea, and coffee on cancer, atheroclerosis, and other diseases are attributed to the antioxidant activity (AOA) of polyphenols, which are abundant in those beverages. We present a rational procedure for determining the total chain-breaking AOA of beverages with the

Kaiware Daikon (Raphanus sativus L.) extract: a naturally multipotent chemopreventive agent.

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Brassica vegetables are attracting major attention as healthy foods because of their content of glucosinolates (GLs) that release the corresponding isothiocyanates (ITCs) upon myrosinase hydrolysis. A number of studies have so far documented the chemopreventive properties of some ITCs. On the other
Pyrrolizidine alkaloid (PA)-containing plants are widespread in the world and are probably the most common poisonous plants affecting livestock, wildlife, and human. PAs require metabolic activation to generate pyrrolic metabolites (dehydro-PAs) that bind cellular protein and DNA, leading to
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