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multiple myeloma/seizures

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Pagina 1 a partire dal 45 risultati

Seizures following sodium sulfate therapy for hypercalcemia in multiple myeloma.

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Intracranial extramedullary hematopoiesis associated with multiple myeloma.

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A 77-year-old woman with multiple myeloma for 5 years presented with obtundation, drowsiness, and disorientation over 15 days. Complete blood count revealed thrombocytopenia (25,000/µL). A brain CT disclosed multiple extraaxial hyperdense foci without bone destruction. Differential diagnosis
Reversible posterior leucoencephalopathy syndrome (RPLS) is a potentially fatal but reversible clinico-radiological syndrome with symptoms of headache, altered mental functioning, visual changes and seizures in association with typical posterior cerebral white matter lesions. RPLS is associated with

CEA-producing multiple myeloma with meningeal invasion during relapse.

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Here we describe the case of a 62-year-old woman diagnosed with multiple myeloma (IgA-κ type) who had a high serum CEA level of 27.7 ng/ml. Upper and lower gastrointestinal endoscopy and PET/CT scan showed no abnormality. After two courses of VAD therapy, the serum CEA level decreased to 5.7 ng/ml,

[Specific meningeal involvement in multiple myeloma].

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Meningeal involvement is extremely rare in multiple myeloma. Its characteristic features can be derived from the 3 cases presented here and from the 11 cases previously published. Specific signs of meningeal myelomatosis include convulsions, confusion, cranial nerve palsies and plasma cells in the

Serum hyperviscosity syndrome associated with multiple myeloma in two cats.

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Serum hyperviscosity syndrome was diagnosed in 2 cats with multiple myeloma. Clinical signs included pale mucous membranes, dehydration, retinal hemorrhages, dilated and tortuous retinal vessels, seizures, head-tilt, nystagmus, systolic murmur, and gallop rhythm. Laboratory abnormalities included
Escalating doses of bortezomib with high-dose melphalan was evaluated as as a conditioning regimen for autologous stem cell transplantation (ASCT) in patients with relapsed or refractory multiple myeloma (MM). MM patients with less than a partial remission (PR) (or 50% reduction) compared to their

Secondary Plasma Cell Leukemia in a Recurrent Multiple Myeloma: Rare Case Scenario

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Plasma cell leukemia (PCL) is an aggressive hematological condition characterized by the presence of plasma cells in the peripheral smear. It presents as de novo or may arise from multiple myeloma (MM), and hence is diagnosed as primary or secondary PCL, respectively. We report a case of 79-year-old

Seizures associated with high-dose intravenous morphine containing sodium bisulfite preservative.

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OBJECTIVE To report a case of seizures occurring during administration of high-dose intravenous morphine containing sodium bisulfite as a preservative. METHODS A 56-year-old woman hospitalized with multiple myeloma developed myoclonic and tonic-clonic seizures following administration of intravenous

Multiple myeloma in sickle cell syndromes.

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Multiple myeloma (MM) is rare among patients with sickle cell syndromes (SCS). We describe six Greek sickle cell patients aged 56 to 65 years: five haemoglobin Sbeta+thalassaemia (HbSbeta+ (thal), one sickle cell anaemia (HbSS), who developed MM (three IgGkappa, one IgGlambda, one IgAkappa, and one
We report three cases of severe hypocalcaemia associated with i.v. bisphosphonate treatment in patients with multiple myeloma. All patients had symptomatic hypocalcaemia, including a tonic-clonic seizure and tachyarrhythmia in one case. Two cases were associated with the development of acute renal

Severe resistant hypocalcemia in multiple myeloma after zoledronic acid administration: a case report.

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BACKGROUND Hypercalcemia is one of the most common metabolic abnormalities encountered in any form of malignancy. Hypocalcemia, however, is a rare manifestation, especially in cancers with bone involvement. Here we present a case of hypocalcemia in a patient with multiple myeloma that was refractory
METHODS Female, 58 FINAL DIAGNOSIS: Listeria septicemia Symptoms: Nausea • vomitting • high fever • apathetic intelligence • repeated convulsion METHODS Levofloxacin Clinical Procedure: - Specialty: Hematology Objective: Rare disease. BACKGROUND Multiple myeloma is a hematological malignancy that

Case study of intracerebral plasmacytoma as an initial presentation of multiple myeloma.

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Cerebral involvement is an uncommon complication of multiple myeloma. We report on a 64-year-old man hospitalized for a partial seizure. MRI showed two intracerebral lesions, which proved to be plasmacytomas. After complete staging, we retained the diagnosis of immunoglobulin G lambda-type multiple
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