Inflammatory Response

Metabolic Disturbance

Immune Suppression

26 g/day freeze-dried powder, 2 weeks duration

Blueberry

Placebo

Acute ingestion of bananas 0.2 g carb/kg every 15 min exercise with water

banana

No banana

North Carolina Research Campus, Human Performance Lab

Blueberries, Bananas, Exercise Recovery

The Combined Influence of Blueberry and Banana Consumption on Metabolic Recovery From 75-km Cycling Exercise Stress

75-km cycling time trial, with or without bananas

Targeted panel of 24 immune proteins including S100A8 and S100A12

Arachadonic acid oxidized derivatives from LC-MS-MS analysis

Appalachian State University

Dole Food Company

Blueberry freeze dried powder or placebo powder

Intervention, water and no banana carbohydrate: consume 3 ml/kg water every 15 min during 75 km cycling

Intervention, banana carbohydrate: ingest 0.2 g carbohydrate/kg body weight from Mini banana with 3 ml/kg water every 15 minutes during 75 km cycling

Intervention, banana carbohydrate: ingest 0.2 g carbohydrate/kg body weight from Cavendish banana with 3 ml/kg water every 15 minutes during 75 km cycling

Intervention: pure banana carbohydrate in sugar beverage; ingest 0.2 g carbohydrate/kg body weight from a 6% sugar beverage every 15 minutes during 75 km cycling (contains 60 grams sugar per liter using the same sugar profile found in Cavendish bananas)

Inflammation

Water

Ingest mini banana containing higher phenolics and carbohydrate concentration

Mini banana

Cavendish banana

Ingest 6% sugar beverage containing same glucose and fructose profile as banana

6% sugar beverage

Human Performance Lab, North Carolina Research Campus

Banana Cultivars and Exercise Performance and Recovery

Influence of Bananas Varying in Carbohydrate and Phenolic Content on Exercise Performance and Recovery

Total plasma concentrations of five inflammatory cytokines [monocyte chemoattractant protein-1 (MCP-1), tumor necrosis factor alpha (TNFα), IL-6, IL-8, and IL-10] will be determined using an electrochemiluminescence based solid-phase sandwich immunoassay (Meso Scale Discovery, Gaithersburg,MD, USA).

change in muscle glycogen using ultrasound

Gastrointestinal and mental symptoms, 1-12 Likert scale

Data will be shared through the Human Metabolome Database (HMDB) or the Scripps Metabolite and Tandem MS Database (METLIN)], other public web sites, and publication in the scientific literature. We will cooperate in making available cloud-based access to the data and associated informatics components within the general scientific community.

The participants will be received a daily regimen of "Kallunk oxide(Immunotherapy)" .

HIV Infections

The study is assigned Arm 1 above 450 cu/mm^3 baseline CD + T cells. HIV type-1 subjects will receive one drug, a daily regimen of "Kallunk oxide(Immunotherapy) + Long Pepper", that is a combination of a traditional alternative medicine (Complementary and Alternative Medicine CAM) as "Kallunk oxide" and appropriate drug carrier antidote. The drug assigns to 5 mg "Kallunk oxide" molecules with1995 mg "Antidote"( This antidote was used as a carrier of "Kallunk oxide" molecules), respectively, for children and adults. Dosage: 2000 mg for children and adults. This powder form sample size product will be administered once daily dose on 7 days treatment. The Botanical name of the antidote is "Piper Longum".

"Kallunk oxide (Immunotherapy) "

Project Site Office, Near Sivan Kovil, Nallepily, Hospital of Integrated Research Site HIRS [new])

Project Site Office, Hospital of Integrated Research Site HIRS(New), Karoor, Ambalapuzha-PO, Alleppey-District, Kerala, India 688561

Project Site Office, Hospital of Integrated Research Site HIRS(New), Ahammed Nagar, Mathura Nagar, Bhingar- PO

Traditional Complementary and Alternative Medicine (CAM) Therapy in the Treatment of HIV/AIDS

Phase III Clinical Studies on Traditional CAM Therapy in the Treatment of HIV/AIDS

Number of participants with adverse events for efficacy by mentioned time frame will be assessed.

musa/nausea

Blueberries, Bananas, Exercise Recovery

Banana Cultivars and Exercise Performance and Recovery

Traditional Complementary and Alternative Medicine (CAM) Therapy in the Treatment of HIV/AIDS

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