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oligosaccharide/emorragia
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Production of oligosaccharide fractions having antithrombotic properties by controlled chemical depolymerization of heparin
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Entra registrati
This invention relates to a physico-chemical process for manufacturing oligosaccharide fractions from commercial heparin having useful pharmaceutical properties, such as: high inhibition of the Xa factor, high antithrombotic, and low anticoagulant activity.
Heparin is a polydisperse polymer of the
Process for the preparation of oligosaccharide fractions by degradation of heparin
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Entra registrati
The present invention refers to a chemical process for the preparation of oligosaccharide fractions having interesting biological activities starting from heparin.
The invention embraces also the so obtained oligosaccharide fractions.
It is known that oligosaccharides and oligosaccharide fractions
Methods of reducing hemorrhage due to surgical procedure
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BACKGROUND OF THE INVENTION
1. Field
The present invention relates to factor VIII glycoforms. In particular, this invention relates to a recombinantly produced factor VIII that has a glycosylation pattern resembling the glycosylation pattern of naturally occurring human Factor VIII.
2.
Method for treating bleeding disorders
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Entra registrati
BACKGROUND OF THE INVENTION
Field
The present invention relates to factor VIII glycoforms. In particular, this invention relates to a recombinantly produced factor VIII that has a glycosylation pattern resembling the glycosylation pattern of naturally occurring human Factor VIII.
Background
Human
Enhancement of thrombolytic therapy with deglycosylated forms of plasminogen
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BACKGROUND
The formation and dissolution of blood clots (thrombi) are the basic processes involved in the physiological response to blood vessel injury. Blood vessel injury triggers a complex and highly regulated series of events that culminates in the cleavage of fibrinogen to fibrin monomers which
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