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Pagina 1 a partire dal 36 risultati
Transient increase of cytoplasmic calcium concentration in the rat hippocampus after kindling-induced seizures. An ultrastructural study with the oxalate-pyro-antimonate technique.
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Kindling stimulations were applied to the Schaffer collateral/commissural fibers in the CA1 area of the dorsal rat hippocampus. In fully kindled animals the ultrastructural distribution of calcium was studied at different time intervals after an induced generalized seizure, using the
Oxalate nephropathy associated with seizures in mink.
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The role of oxalate in star fruit neurotoxicity of five-sixths nephrectomized rats.
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To investigate the role of oxalate in star fruit neurotoxicity, rats were given star fruit or oxalate after a sham operation or modified five-sixths nephrectomy; namely, star fruit (SC) or oxalate (OxC) for sham-operated rats and star fruit (SNx), calcium gluconate treated star fruit juice (SCaNx),
Kainic acid seizures and the reversibility of calcium loading in vulnerable neurons in the hippocampus.
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The threshold pathological changes in the rat hippocampus following systemic administration of kainic acid (12-15 mg/kg) have been studied in relation to i the duration of EEG seizure activity and ii calcium accumulation in post-synaptic neurons, using the oxalate-pyroantimonate method. The
Neurotoxic effects of carambola in rats: the role of oxalate.
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OBJECTIVE
Carambola (star fruit) has been reported to contain neurotoxins that cause convulsions, hiccups, or death in uremic patients, and prolong barbiturate-induced sleeping time in rats. The constituent responsible for these effects remains uncertain. Carambola contains a large quantity of
Calcium in hippocampus following lidocaine induced seizures: an electron cytochemical study.
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The effect of lidocaine seizures on cellular accumulation of calcium was studied in hippocampal subfields CA1 and CA3 and the dentate gyrus of rats, using the combined oxalate-pyroantimonate method. The specificity of the reaction was ascertained by EGTA treatment and X-ray microanalysis. In control
[Cerebrorenal oxalate formation--a metabolic abnormality following parenteral infusions of carbohydrate exchange substances].
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A 46 years old male alcoholic was admitted with an assumed alcohol withdrawal syndrome accompanied by tonic-clonic seizures. Parenteral nutrition with fructose, sorbitol, xylitol, dextran, hydroxyethylstarch, electrolytes, vitamins and amino acids was undertaken. He died 20 d later due to renal
RESTORATIVE EFFECT OF SALTS OF MAGNESIUM AND CALCIUM AFTER LETHAL DOSES OF SODIUM OXALATE.
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The experiments presented in this paper brought out the following facts. Intramuscular injections of sodium oxalate into rabbits in doses of 0.18 and 0.2 gm. proved to be invariably fatal, death generally occurring in a comparatively short time. The symptoms consisted in excitation and tonic and
Oxalate-crystals in different tissues following intoxication with ethylene glycol: three case reports.
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Three alcoholics (62 years, 47 years, 83 years) died between 11 and 18 h after ingestion of ethylene glycol (EG). One person committed suicide. Observed symptoms of intoxication were seizures, respiratory depression, arrhythmias and hypotonia. All died in hospital after failed attempts at
Effects of the selective sigma receptor ligand, 1-(2-phenethyl)piperidine oxalate (AC927), on the behavioral and toxic effects of cocaine.
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BACKGROUND
Sigma receptors represent a unique structural class of proteins and they have become increasingly studied as viable medication development targets for neurological and psychiatric disorders, including drug abuse. Earlier studies have shown that cocaine and many other abused substances
Intracellular calcium accumulation in rat hippocampus during seizures induced by bicuculline or L-allylglycine.
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Using electron microscopy and the combined oxalate-pyroantimonate technique, free calcium ions were located in the hippocampus of control rats and of those that had undergone status epilepticus induced by L-allylglycine or bicuculline. The validity of this technique was established by the use of the
Accumulation of calcium in the rat hippocampus during kainic acid seizures.
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The change in the total calcium content of the rat hippocampus was investigated quantitatively and the sites of the accumulated calcium in the CA1 region were demonstrated cytochemically by the oxalate-pyroantimonate technique 4 h following intraperitoneal kainic acid administration. Kainic acid was
Ethylene glycol: an estimate of tolerable levels of exposure based on a review of animal and human data.
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Upon ingestion ethylene glycol (EG, monoethylene glycol) is rapidly absorbed from the gastrointestinal tract, and depending on the severity of exposure signs of toxicity may progress through three stages. Neurological effects characterize the first step consisting of central nervous depression
Urolithiasis associated with topiramate.
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OBJECTIVE
Topiramate is a sulfamate-substituted monosaccharide anticonvulsant used as adjunctive therapy for intractable refractory seizures. It is report a case of topiramate-induced urolithiasis.
METHODS
A 35-year-old man presented with acute, right-sided, colicky flank pain. He denied hematuria
Reversibility of Severe Cerebral Magnetic Resonance Imaging Changes Associated with Ethylene Glycol Toxicity.
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Ethylene glycol (EG), commonly found in antifreeze and deicing solutions, continues to be a cause of morbidity and mortality in the pediatric population. EG metabolism produces toxins that cause metabolic acidosis and calcium oxalate deposition throughout the body. Deposition in the central nervous
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