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parasitemia/solanum

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In vivo antimalarial activities of glycoalkaloids isolated from Solanaceae plants.

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BACKGROUND Malaria is one of the most common and serious protozoan tropical diseases. Multi-drug resistance remains pervasive, necessitating the continuous development of new antimalarial agents. OBJECTIVE Many glycosides, such as triterpenoid saponins, were shown to have antimalarial activity

Diosgenone synthesis, anti-malarial activity and QSAR of analogues of this natural product.

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Solanum nudum Dunal steroids have been reported as being antimalarial compounds; however, their concentration in plants is low, meaning that the species could be threatened by over-harvesting for this purpose. Swern oxidation was used for hemisynthesis of diosgenone (one of the most active steroidal

Antiplasmodial potential of medicinal plant extracts from Malaiyur and Javadhu hills of South India.

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The emergence and spread of Plasmodium falciparum with resistance to chloroquine (CQ), the safest and cheapest anti-malarial drug, coupled with the increasing cost of alternative drugs especially in developing countries have necessitated the urgent need to tap the potential of plants for novel

Antimalarial evaluation of selected medicinal plant extracts used in Iranian traditional medicine.

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OBJECTIVE In an attempt to discover new natural active extracts against malaria parasites, the present study evaluated the antiplasmodial properties of selected plants based on Iranian traditional medicine. METHODS Ten plant species found in Iran were selected and collected based on the available
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