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parthenolide/edema
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6 risultati
Parthenolide ameliorates intracerebral hemorrhage-induced brain injury in rats.
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Neuroinflammation and oxidative stress are key contributors to intracranial hemorrhage (ICH)-induced brain injury. Parthenolide (PN) is a sesquiterpene lactone that has been observed to have antioxidative, anti-inflammatory, and neuroprotective potentials. However, the role of PN in ICH remains
Antinociceptive and anti-inflammatory effects of Tanacetum parthenium L. extract in mice and rats.
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Oral administration of the feverfew (Tanacetum parthenium) extract led to significant antinociceptive and anti-inflammatory effects against acetic acid-induced writhing in mice and carrageenan-induced paw edema in rats, respectively. These responses were dose-dependent (10, 20, 40 mg/kg, p.o.).
High-mobility group box 1 up-regulates aquaporin 4 expression via microglia-astrocyte interaction.
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To clarify the mechanism of high-mobility group box (HMGB) 1-induced brain edema formation, this study focused on the effect of HMGB1 on aquaporin (AQP) 4, a water channel, in rat brain. Treatments for 6h with 100-1000ng/ml HMGB1, not showing self-toxicity, of primary-cultured rat astrocytes didnot
Fraxinellone inhibits inflammatory cell infiltration during acute pancreatitis by suppressing inflammasome activation.
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Inflammasomes promote the production of pro-inflammatory cytokines, such as interleukin (IL)-1β and IL-18, which are the representative mediators of inflammation. Abnormal activation of inflammasomes leads to the development of inflammatory diseases such as acute pancreatitis (AP). In this study, we
Bioactivity screening of five Centaurea species and in vivo anti-inflammatory activity of C. athoa.
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BACKGROUND
Centaurea L. (Asteraceae) species used as herbal remedies in Turkish traditional medicine have shown several biological properties.
OBJECTIVE
Extracts obtained from the aerial parts of Centaurea aphrodisea Boiss., Centaurea athoa DC., Centaurea hyalolepis Boiss., Centaurea iberica Trev.
Anti-inflammatory and anti-hyperalgesic effects of sesquiterpene lactones from Magnolia and Bear's foot.
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Sesquiterpene lactones possess a variety of biological activities, including anti-inflammatory activity. Two plants native to the southeastern United States, Magnolia grandiflora (L.) and Smallanthus uvedalius (L.) [syn Polymnia uvedalius (L.)], are novel sources of the sesquiterpene lactones
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