A backboard with internal ducts for circulation of heated and/or cooled liquid or gas for treating a post-traumatic-injury patient, specifically a patient with a severe back injury. The backboard provides three vital functions for the patient: (1) immobilization (2) maintaining body core temperature, and (3) reduction/prevention of inflammation and/or edema. The thermally-interactive unit is constructed of radiolucent materials for compatibility with x-ray equipment, and is compatible with sterilization requirements.

Thermally-interactive backboard

The present invention is concerned with deuterium-enriched pyrimidine compounds of formula I, their derivatives and pharmaceutically acceptable salts and methods of use thereof, ##STR00001## The compounds of formula I are useful for the prevention and treatment of liver fibrosis and cirrhosis, hepatocellular carcinoma, neuroendrcrine neoplasia including metastasis and fibrosis fibrotic processes associated with neuroendocrine cell dysregulation for example Crohn's disease, pulmonary arterial hypertension, pulmonary hypertension associated with chronic obstructive pulmonary disease (COPD), right ventricular hypertrophy, pulmonary vascular remodeling, asthma, cystic fibrosis, hypertension, ischemic stroke, angina pectoris, congestive heart failure, arrhythmia, arterial fibrillation, gastrointestinal disorders, anxiety, depression, stress disorders, post-traumatic stress disorder, obsessive compulsive disorders, demyelinating diseases, acute or chronic cerebrovascular damage, cerebral infarction, subarachanoid hemorrhage, and cerebral edema, neuropathological diseases and cardiovascular system regulation.

post-traumatic stress disorder/edema

Thermally-interactive backboard

Deuterium-enriched pyrimidine compounds and derivatives

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