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post-traumatic stress disorder/seizures
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Compositions and methods for the treatment of epilepsy and neurological diseases
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PRIORITY
The present application claims the benefit of Indian Provisional Patent Application No. 3701/CHE/2012 filed on 6 Sep. 2012 and the International Application No. PCT/IB2013/056683 filed on 16 Aug. 2013, the entire disclosure of which is relied on for all purposes and is incorporated into
Compositions and methods for the treatment of epilepsy
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PRIORITY
This application is a national phase filing of the Patent Cooperation Treaty (PCT) application # PCT/IB2013/050740 titled "COMPOSITIONS AND METHODS FOR THE TREATMENT OF EPILEPSY" filed on Jan. 29, 2013. Published with WIPO Publication # WO/2013/167986 which further claims priority to patent
Derivatives of rufinamide and their use in inhibtion of the activation of human voltage-gated sodium channels
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BACKGROUND OF THE INVENTION
Lennox-Gastaut Syndrome (LGS) is a severe pediatric epilepsy disorder associated with various types of seizures and cognitive dysfunction that persist into adulthood. As a result, LGS patients suffer from varying degrees of learning disabilities, psychiatric disorders,
Rufinamide and derivatives and their use in modulating the gating process of human voltage-gated sodium channels
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BACKGROUND OF THE INVENTION
Lennox-Gastaut Syndrome (LGS) is a severe pediatric epilepsy disorder associated with various types of seizures and cognitive dysfunction that persist into adulthood. As a result, LGS patients suffer from varying degrees of learning disabilities, psychiatric disorders,
Compositions and methods for the treatment of neurological disorders
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PRIORITY
This application is a national phase filing of the Patent Cooperation Treaty (PCT) application #PCT/IB2013/050711 titled "COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS" filed on Jan. 28, 2013 Published with WIPO Publication #WO/2013/167985, which further claims
Ethinyl-pyrazole derivative
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CROSS REFERENCE TO RELATED APPLICATIONS
This application is a National Stage of International Application No. PCT/JP2011/067394 filed Jul. 29, 2011, claiming priority based on Japanese Patent Application No. 2010-170732 filed Jul. 29, 2010, the contents of all of which are incorporated herein by
7-piperidinoalkyl-3, 4-Dihydroquinolone derivative
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CROSS REFERENCE TO RELATED APPLICATIONS
This is a National Stage of International Application No. PCT/JP2009/067441 filed Sep. 30, 2009, claiming priority based on Japanese Patent Application No. 2008-257072 filed Oct. 2, 2008, the contents of all of which are incorporated herein by reference in
Deuterium-enriched alkyl sulfonamides and uses thereof
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FIELD OF THE INVENTION
The present invention generally relates to deuterium-enriched N-acetylamino-(piperazinyl)-butyl)-alkylsulfonamides of formula 1, their pharmaceutically acceptable salts, synthesis and methods of use thereof. These compounds are 5-HT (serotonin) receptor modulators more
Piperazinyl-propyl-pyrazole derivatives as dopamine D4 receptor antagonists, and pharmaceutical compositions containing the same
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CROSS REFERENCE TO RELATED APPLICATION
This application claims the priority of Korean Patent Application No. 10-2007-0022845, filed on Mar. 8, 2007 in the KIPO (Korean Intellectual Property Office), the disclosure of which are incorporated herein in their entirety by reference. Further, this
Piperazinyl-propyl-pyrazole derivatives as dopamine D4 receptor antagonists, and pharmaceutical compositions containing the same
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TECHNICAL FIELD
The present invention relates to a piperazinyl-propyl-pyrazole derivative, a method of its preparation and a pharmaceutically acceptable salt comprising the same.
BACKGROUND ART
Dopamine is a neurotransmitter essential for neuronal signal transduction in animal brains including
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