each patient will be submitted to : swan-ganze catheterization detailed echocardiography blood sample for biomarkers (troponin, uric acid and micro RNA)

Pulmonary Hypertension

Right heart catheterization and mixed venous blood samples will be obtained for ABG, biomarkers (troponin , uric acid and micro RNA).
Each subject will have echocardiography, 6 MWD, clinical functional class and blood sample at the day of right heart catheterization or at least less than week of right heart catheterization

swan ganze catheter /echocardiography

Evaluation of Echocardiographic Indices and Blood Biomarkers in Group 1 Pulmonary Hypertension

All trans thoracic echocardiographic indices will be measured:
peak tricuspid regurgitation velocity (m/s). right ventricular outflow acceleration time (msec). peak early pulmonary regurgitation velocity (m/s). peak late pulmonary regurgitation velocity (m/s) . tricuspid regurgitation time velocity integral (m/s). tricuspid annulus tissue Doppler image . right ventricle morphology and functions. left ventricle morphology and functions.

Blood samples from pulmonary circulation will be obtained for troponin level

Blood samples from pulmonary circulation will be obtained for serum uric acid.

Blood samples from pulmonary circulation will be obtained for mRNA level

Moustafa Hosny Abdelmegeed Aly

Principal Investigator

Assiut University

patients with primary pulmonary hypertension will submitted to : swanganz cath. detailed echocadiography blood samples for bio markers

All pediatric patients who present to pediatric cardiothoracic unit, Assiut University Hospital and who meet the listed inclusion and exclusion criteria will be eligible for the study. Patients' charts will be retrieved based on their surgical procedures. The charts will be reviewed and eligible patients will be filtered. The needed variables will be entered into our data base for later data analysis

Tetralogy of Fallot

Early Right Ventricular Function After Repair Of Tetralogy Of Fallot , An Evidence Based Study.

the study aim to assess the function of the Right ventricle early after surgical repair of tetralogy of fallot by echocardiography.

the study aim to follow up the function of the Right ventricle after surgical repair of tetralogy of fallot by echocardiography

This study aims to assessing right ventricular function early after surgical repair of tetralogy of Fallot and identifying the risk factors associated with development of RV dysfunction.

pulmonary valve insufficiency/hypoxia

Evaluation of Echocardiographic Indices and Blood Biomarkers in Group 1 Pulmonary Hypertension

Early Right Ventricular Function After Repair Of Tetralogy Of Fallot , An Evidence Based Study.

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