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Pagina 1 a partire dal 18 risultati
Low density, good flowability cyclodextrin-raffinose binary carrier for dry powder inhaler: anti-hygroscopicity and aerosolization performance enhancement.
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BACKGROUND
The hygroscopicity of raffinose carrier for dry powder inhaler (DPI) was the main obstacle for its further application. Hygroscopicity-induced agglomeration would cause deterioration of aerosolization performance of raffinose, undermining the delivery
Brain Barrier Disruption and Region-Specific Neuronal Degeneration during Necrotizing Enterocolitis in Preterm Pigs.
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Necrotizing enterocolitis (NEC) increases the risk of brain injury and impaired neurodevelopment. Rapid brain maturation prior to birth may explain why preterm brains are particularly vulnerable to serious infections. Using pigs as models, we hypothesized that preterm birth was associated with
Deciphering the metabolic pathways influencing heat and cold responses during post-harvest physiology of peach fruit.
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Peaches are highly perishable and deteriorate quickly at ambient temperature. Cold storage is commonly used to prevent fruit decay; however, it affects fruit quality causing physiological disorders collectively termed 'chilling injury' (CI). To prevent or ameliorate CI, heat treatment is often
The effect of branched-chain amino acid-enriched parenteral nutrition on gut permeability.
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In situations of catabolic stress, the gut becomes atrophic and has a diminished barrier function as evidenced by an increased permeability to a variety of molecules. It is known that the parenteral administration of branched-chain amino acids (BCAA) reduce gut atrophy. The aim of this study was to
Screening of lactic acid bacteria from Indonesia reveals glucansucrase and fructansucrase genes in two different Weissella confusa strains from soya.
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Homopolysaccharide (glucan and fructan) synthesis from sucrose by sucrase enzymes in lactic acid bacteria (LAB) has been well studied in the genera Leuconostoc, Streptococcus and Lactobacillus. This study aimed to identify and characterize genes encoding glucansucrase/glucosyltransferase (GTF) and
Compositional analysis of a modified University of Wisconsin solution for extended myocardial preservation. A study of the left ventricular pressure-volume relation.
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BACKGROUND
The University of Wisconsin solution (UW) has been shown to be superior to the use of traditional types of simple crystalloids in extended heart preservation. This study was designed to determine the necessity of four potentially redundant components in UW.
METHODS
Forty canine hearts (n
Isolation of a CDC28 homologue from Cryptococcus neoformans that is able to complement cdc28 temperature-sensitive mutants of Saccharomyces cerevisiae.
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A partial cDNA fragment of the Cryptococcus neoformans homologue of the main cell cycle control gene CDC28/cdc2 was isolated using degenerate primer RT-PCR. A subsequent search in the C. neoformans genome database identified several sequences similar to CDC28/cdc2. A part of the sequence which
Spray drying from organic solvents to prepare nanoporous/nanoparticulate microparticles of protein: excipient composites designed for oral inhalation.
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OBJECTIVE
The aim of this study was to determine if spray-drying could successfully produce microparticles containing the model protein trypsin in a form suitable for inhalation.
METHODS
Trypsin was spray-dried with raffinose from a methanol : n-butyl acetate solvent system (MeOH : BA). The solvent
[A novel alpha-galactosidase from Arthrobacter sp. GN14 isolated from Grus nigricollis feces: gene cloning, heterologous expression and characterization].
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OBJECTIVE
Cloning and heterologously expressing the alpha-galactosidase gene (agaAGN14) from Arthrobacter sp. GN14 isolated from feces of black-neck crane (Grus nigricollis).
METHODS
The full-length agaAGN14 was cloned based on degenerate PCR and GC TAIL-PCR (thermal asymmetric interlaced PCR),
THE INFLUENCE OF CARBOHYDRATES ON THE CULTIVATION OF SPIROCHETES.
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Various carbohydrates have been added to the fluid cultures of different strains of spirochetes in order to determine the behavior of the latter toward the carbohydrates. In the present experiment, amygdalin, arabinose, beerwort, dextrin, galactose, glycogen, glucose, inulin, lactose, levulose,
STUDIES IN BOVINE MASTITIS : I. NON-HEMOLYTIC STREPTOCOCCI IN INFLAMMATION OF THE UDDER.
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It seems clearly established that non-hemolytic streptococci are responsible for a considerable number of cases of bovine mastitis. Of the 81 animals examined, 31 were suffering from infections of this type. The lesions produced in invaded quarters varied from an involvement of only the lining
Sugar feeding by the aphid parasitoid Binodoxys communis: how does honeydew compare with other sugar sources?
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Parasitoids commonly forage in agricultural settings where the predominant sugar source is homopteran honeydew. The aphidiine braconid, Binodoxys communis, is an Asian parasitoid currently being released against the soybean aphid, Aphis glycines, in North American soybean fields. We conducted a
Effects of electron-beam radiation on nutritional parameters of Portuguese chestnuts (Castanea sativa Mill.).
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Chestnuts are a widely consumed fruit around the world, with Portugal being the fourth biggest producer in Europe. Storage of these nuts is an important step during processing, and the most widely used fumigant was banned in the European Union under the Montreal Protocol because of its toxicity.
Unraveling Key Metabolomic Alterations in Wheat Embryos Derived from Freshly Harvested and Water-Imbibed Seeds of Two Wheat Cultivars with Contrasting Dormancy Status.
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Untimely rains in wheat fields during harvest season can cause pre-harvest sprouting (PHS), which deteriorates the yield and quality of wheat crop. Metabolic homeostasis of the embryo plays a role in seed dormancy, determining the status of the maturing grains either as dormant (PHS-tolerant) or
Changes in oligosaccharide content and antioxidant enzyme activities in developing bean seeds as related to acquisition of drying tolerance and seed quality.
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Seeds of bean (Phaseolus vulgaris cv. Vernel) were collected throughout their development on the plant and dried at 15 degrees C and 75% relative humidity to a final moisture content of about 16% (fresh weight basis) to determine whether the onset of tolerance to this drying condition was related to
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