respiratory insufficiency/cannabis

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"Smoking wet": respiratory failure related to smoking tainted marijuana cigarettes.

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Reports have suggested that the use of a dangerously tainted form of marijuana, referred to in the vernacular as "wet" or "fry," has increased. Marijuana cigarettes are dipped into or laced with other substances, typically formaldehyde, phencyclidine, or both. Inhaling smoke from these cigarettes

Cannabinoid suppressed bicuculline-induced convulsion without respiratory depression in the brainstem-spinal cord preparation from newborn rats.

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Previous studies have suggested that cannabinoid compounds are anticonvulsants and that these compounds depress respiratory activity. However, the anticonvulsant potential of cannabinoids and their depressive effect on respiration have not been evaluated simultaneously. In the present study, we used

Synthetic cannabis and respiratory depression.

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In recent years, synthetic cannabis use has been increasing in appeal among adolescents, and its use is now at a 30 year peak among high school seniors. The constituents of synthetic cannabis are difficult to monitor, given the drug's easy accessibility. Currently, 40 U.S. states have banned the

Synthetic cannabinoid induced acute respiratory depression: Case series and literature review.

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Synthetic Cannabinoids are a street drug that is widely attainable and cheap compared to natural cannabis, and has variable potency and unpredictable effects with no commercially available diagnostic test to confirm its presence. Similar to natural cannabis, Synthetic Cannabinoid intoxication can

Acute Eosinophilic Pneumonia with Respiratory Failure Induced by Synthetic Cannabinoid Inhalation.

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BACKGROUND In recent days, synthetic cannabinoid derivatives have become life threatening for young people. Here, we want to share a case of acute eosinophilic pneumonia triggered by inhalation of synthetic cannabinoid, new side effects of which are being detected day by day. METHODS A 21-year-old

The blind men and the elephant: Systematic review of systematic reviews of cannabis use related health harms.

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Cannabis is the third most used psychoactive substance worldwide. The legal status of cannabis is changing in many Western countries, while we have very limited knowledge of the public health impact of cannabis-related harms. There is a need for a summary of the evidence of harms and risks

Retrospective Chart Review of Synthetic Cannabinoid Intoxication with Toxicologic Analysis.

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UNASSIGNED Use of synthetic cannabinoids (SC) has recently emerged as a new drug epidemic. Our emergency departments (EDs) received a surge of SC users presenting with lethargy and bradycardia, contrasting prior reports of SC-induced tachycardia and agitation. Our goal was to describe these novel

Acute intoxication of four individuals following use of the synthetic cannabinoid MAB-CHMINACA.

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BACKGROUND The largest group of new psychoactive substances (NPS) are synthetic cannabinoids (SC). Those that become controlled are immediately replaced by new uncontrolled substances. The recent resurgence of the NPS market in Poland resulted in a further amendment to the Drug Addiction

Spice-y Kidney Failure: A Case Report and Systematic Review of Acute Kidney Injury Attributable to the Use of Synthetic Cannabis.

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BACKGROUND Spice is a synthetic cannabinoid that is readily available for purchase in smoke shops at relatively low cost. Spice is not detectable upon routine drug screening, making it an increasingly popular new street drug. METHODS A 21-year-old man presented with new-onset seizures. During the

A urinary test procedure for identification of cannabidiol in patients undergoing medical therapy with marijuana.

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Marijuana is classified by the Drug Enforcement Agency (DEA) as Schedule I, drugs having no accepted medical value. Twenty-three states and the District of Columbia have legalized medical marijuana. This conflict inhibits physicians from prescribing marijuana and the systematic study of marijuana in

Critical Illness Secondary to Synthetic Cannabinoid Ingestion

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Importance: Synthetic cannabinoids (SCs), commonly known as K2, spice, or fake weed, are cheap, artificially manufactured recreational drugs that have emerged as a major public health threat in various regions of the US.

"Just one bad high:" considering synthetic cannabinoid outcome expectancies in adolescents.

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OBJECTIVE Certain medical consequences seem unique to synthetic cannabinoid (SC) and not cannabis use. We report the case of an adolescent, whose drug expectancies appear to minimize the severity of SC-related adverse events. RESULTS An 18-year-old male presented with altered mental status and

Tolerance to the respiratory effects of marijuana in man.

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The respiratory depressant effect of marijuana was studied by means of carbon dioxide respiratory response curves in eight healthy male subjects participating in a study of the effects of a 90-day ad libitum intoxication to marijuana. Subjects were studied in the morning after refraining from

[Alveolar haemorrhage following a cannabis water pipe].

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Respiratory toxicity of cannabis is well-known today particularly with the new consumption patterns. We report the case of a 25-year-old man admitted for haemoptysis, with unfavourable outcome and acute respiratory failure. Various explorations concluded to acute respiratory distress syndrome

Role of endocannabinoids and cannabinoid-1 receptors in cerebrocortical blood flow regulation.

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BACKGROUND Endocannabinoids are among the most intensively studied lipid mediators of cardiovascular functions. In the present study the effects of decreased and increased activity of the endocannabinoid system (achieved by cannabinoid-1 (CB1) receptor blockade and inhibition of cannabinoid

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