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5 risultati
Serotonin involvement in Rhodiola rosea attenuation of nicotine withdrawal signs in rats.
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Rhodiola rosea has been used for centuries in the traditional medicine to stimulate nervous system, to enhance physical and mental performance and to treat fatigue. It is known that administration of Rhodiola rosea extract elicits antidepressant activity, but the mechanism of action still remains
Evaluation of Rhodiola rosea L. extract on affective and physical signs of nicotine withdrawal in mice.
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The aim of the present study was to investigate the effects of a Rhodiola rosea L. extract on the prevention of the development of nicotine dependence and for the reduction of abstinence suffering following nicotine cessation in mice. Dependence was induced in mice by subcutaneous injections of
Rhodiola rosea L. extract and its active compound salidroside antagonized both induction and reinstatement of nicotine place preference in mice.
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BACKGROUND
Conventional pharmacological treatments for drug addiction aim to reduce three most important aspects: withdrawal syndrome, craving, and relapse. Pharmacological treatments currently available for the treatment of tobacco smoking are able to alleviate withdrawal symptoms but are not
[Construction of expression vector driven by tobacco root-specific promoter and transformation into Rhodiola hairy root].
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OBJECTIVE
To construct root-specific promoter of plant expression vector and transformate into Rhodiola hairy root.
METHODS
The expression vector pCA-Tob7: UGTR, driven by tobacco root-specific promoter TobRB7, was constructed from pCAM-BIA1301 by substituting the CaMV 35S promoter and GUS gene with
Complete Pathway Elucidation and Heterologous Reconstitution of Rhodiola Salidroside Biosynthesis.
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Salidroside is a bioactive tyrosine-derived phenolic natural product found in medicinal plants under the Rhodiola genus. In addition to their anti-fatigue and anti-anoxia roles in traditional medicine, Rhodiola total extract and salidroside have also displayed medicinal properties as
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