Scopolamine 1.5 milligram(mg) patch Propofol infusion remifentanil infusion 250mg erythromycin po for 2 doses Solumedrol 0.625mg IV droperidol 4mg IV Ondansetron Ketorolac 30mg IV ibuprofen 600mg po q6h Fentanyl Hydrocodone/Tylenol po

This arm was managed perioperatively with the protocol.

Intervention Cohort

This arm was a retrospective comparison cohort treated at the same institution, managed per provider preference prior to protocol implementation.

Comparison Cohort

Total

Sex: Female, Male

End of surgery time determined by anesthesia portion of the medical record. PONV to be assessed by review of surgeons' and nurses' notes in the medical record as well as through review of patient diaries. Vomiting constitutes a safety issue and, as such, associated adverse events will be noted.

Patients undergoing maxillary surgery using the antiemetic anesthetic protocol

Post-operative Nausea

Anesthesia start time determined from anesthesia portion of the medical record. Time at which discharge order was placed will serve as time of discharge.

Hospital Length of Stay

To be assessed based on patient diary completed daily for 1 week following discharge to home from the hospital

Patients undergoing maxillary surgery using the antiemetic anesthetic protocol who completed the post-discharge diary.

This arm was a retrospective comparison cohort treated at the same institution, managed per provider preference prior to protocol implementation, who completed the post-discharge diary

Post-discharge Nausea

Post-operative Vomiting

Patients undergoing maxillary surgery using the antiemetic anesthetic protocol who completed the post-discharge diary

Post-discharge Vomiting

Patients undergoing maxillary surgery using antiemetic anesthesia protocol

Overall Study

Dr. Jay Anderson, PI

Patients undergoing maxillary surgery using the antiemetic anesthesia protocol

Nausea Persistent

Intervention group consisted of patients undergoing maxillary osteotomy who received an antiemetic protocol designed to provide multimodal antiemetic therapy which have been shown to help prevent and/or treat postoperative nausea, combined with the elimination of anesthetic factors that may contribute to postoperative nausea and vomiting.

Antiemetic anesthesia protocol

UNC-Chapel Hill

Study of Anesthesia Techniques to Reduce Nausea and Vomiting After Jaw Corrective Surgery

A Prospective Evaluation of an Anesthesia Protocol to Reduce Post-operative and Post-discharge Nausea and Vomiting in a High Risk Orthognathic Surgery Population

University of North Carolina, Chapel Hill

National Institute of Dental and Craniofacial Research (NIDCR)

Postoperative Nausea and Vomiting

Caffeine

Beth Israel Deaconess Medical Center

Caffeine in the Prevention of Post-operative Nausea and Vomiting

A Prospective, Randomized, Double-blind, Placebo-controlled Study of Caffeine in the Prevention of Post-operative Nausea and Vomiting in Patients Undergoing Ambulatory Surgery Under General Anesthesia

scopolamine/cefalea

Study of Anesthesia Techniques to Reduce Nausea and Vomiting After Jaw Corrective Surgery

Caffeine in the Prevention of Post-operative Nausea and Vomiting

Il database di erbe medicinali più completo supportato dalla scienza