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senecionine/senecio

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ArticoliTest cliniciBrevetti
Pagina 1 a partire dal 51 risultati

[Simultaneous quantitation of adonifoline and senecionine in Senecio herbs by UPLC-MS].

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OBJECTIVE To develop an UPLC-MS method for the simultaneously quantitation of adonifoline and senecinine in Senecio herbs. METHODS UPLC-Micro 2000 was used for quantification in SIR mode under ESI+. Monocrotaline was used as the internal standard. Chromatography was performed on a Shiseido Capcell

Identification of senecionine and senecionine N-oxide as antifertility constituents in Senecio vulgaris.

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The MeOH extract of Senecio vulgaris L., administered po to rats on Days 1-10 postcoitum, significantly decreased the number of normal fetuses per pregnant rat found at autopsy on Day 16. Additional experiments showed a similar activity for its hepatotoxic constituents senecionine and senecionine

Senecionine, Seneciphylline, Jacobine and Otosenine from Senecio cineraria.

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Tumor inhibitors. XXII. Senecionine and senecionine N-oxide, the active principles of Senecio triangularis.

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In this study we investigated the effect of methyl jasmonate (MeJA) application on pyrrolizidine alkaloid (PA) concentration and composition of two closely related Jacobaea species. In addition, we examined whether MeJA application affected herbivory of the polyphagous leaf feeding herbivore

The toxicity of Senecio inaequidens DC.

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This study was designed to confirm the toxicity of a plant implicated in an outbreak of poisoning of stock in Frankfort, Free State Province, South Africa. Cows died acutely after being introduced into a camp, where an abundant, green shrublet was noted to be heavily grazed. This plant was

Determination of pyrrolizidine alkaloids in Senecio inaequidens D.C. by capillary gas chromatography.

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A study of the toxic pyrrolizidine alkaloids contained in Senecio inaequidens D.C., an infestant species of the Senecio genus, widespread in the North East of Italy, is reported. Five of these compounds, senecivernine, senecionine, integerrimine, retrorsine and an analogue of retrorsine, were

[Ethyl acetate-soluble chemical constituents from whole plants of Senecio chrysanthemoides].

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OBJECTIVE To investigate the chemical constituents from the whole plants of Senecio chrysanthemoides. METHODS The chemical constituents were isolated and purified by chromatographic techniques over silica gel, Sephadex LH-20, preparative TLC and preparative HPLC. Structures of the compounds were

Alkaloids from Senecio aegyptius and S. desfontainei.

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Otosenine and senecionine/seneciphyllme were isolated from Senecio aegyptius and S. desfontainei, respectively. Senecionine and seneciphylline easily cocrystallize; m.p. and IR-spectra of mixtures of both alkaloids and their separation by PC are described. IR evidence of individual alkaloids and of
The metabolism in vitro of four pyrrolizidine alkaloids from the poisonous plant Senecio jacobaea was studied. The pyrrolizidine alkaloids jacobine, jacoline, senecionine, and seneciphylline, all macrocyclic diesters of retronecine, were incubated with rat liver microsomes. Analysis of incubation

Influence of grass pellet production on pyrrolizidine alkaloids occurring in Senecio aquaticus-infested grassland.

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1,2-Dehydro-pyrrolizidine alkaloids (PA) and their N-oxides (PANO) exhibit acute and chronic toxic effects on the liver and other organs and therefore are a hazard for animal and human health. In certain regions of Germany, an increasing spread of Senecio spp. (ragwort) on grassland and farmland

Variation in pyrrolizidine alkaloid patterns of Senecio jacobaea.

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We studied the variation in pyrrolizidine alkaloid (PA) patterns of lab-grown vegetative plants of 11 European Senecio jacobaea populations. Plants were classified as jacobine, erucifoline, mixed or senecionine chemotypes based on presence and absence of the PAs jacobine or erucifoline. Due to the

Comparison of the toxicities of Senecio jacobaea, Senecio vulgaris and Senecio glabellus in rats.

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The toxicity of Senecio jacobaea, S. vulgaris and S. glabellus to rats was assessed in a feeding trial. The plants were of similar toxicity, with a plant dry matter intake of about 20% of initial body weight being a lethal dose. Gas chromatography-mass spectrometry analysis demonstrated the presence
Segregating plant hybrids often have more ecological and molecular variability compared to parental species, and are therefore useful for studying relationships between different traits, and the adaptive significance of trait variation. Hybrid systems have been used to study the relationship between

Determination of pyrrolizidine alkaloids in honey from selected sites by solid phase extraction and HPLC-MS.

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A method was developed for the determination in honey of the Ragwort (Senecio jacobaea) derived pyrrolizidine alkaloids jacoline, jacozine, jacobine, seneciphylline and senecionine, combining solid-phase extraction with high performance liquid chromatography and atmospheric pressure chemical
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