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sertoli cell tumor/femminilizzazione
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A case report of Sertoli cell tumor in a patient with testicular feminization: many dilemmas for the pathologist.
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OBJECTIVE
The aim of this case report is to present the pathological, clinical, and ethic problems due to the diagnosis of an adnexal mass in a female patient with an undetected androgen insensitivity syndrome.
METHODS
We employed both commonly used pathologic techniques, such as hematoxylin-eosin
Simultaneous sertoli cell tumor and adenocarcinoma of the tunica vaginalis testis in a patient with testicular feminization.
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BACKGROUND
The association of testicular feminization with late diagnosis in a patient with a large Sertoli cell tumor and a metastasizing adenocarcinoma of the tunica vaginalis testis is unusual.
METHODS
Testicular feminization was diagnosed in a 72-year-old patient, who was admitted with a large
Bilateral Sertoli cell tumor of testes with feminizing and masculinizing activity occurring in a child.
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A case of an unusual, histologically atypical, bilateral Sertoli cell tumor of testis, in association with masculinization and feminization effects, that occurring in a 5-year-old boy, is presented. Although Sertoli cell tumors are not infrequent, this case is morphologically and endocrinologically
Bone marrow hypoplasia in eight dogs with Sertoli cell tumor.
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Eight male dogs with Sertoli cell tumor had pancytopenia and bone marrow hypoplasia attributed to endogenous estrogen myelotoxicosis. Clinical signs were hemorrhage caused by thrombocytopenia, anemia caused by blood loss or diminished erythrocyte production, and infection and fever associated with
Prostatic cyst and concurrent Sertoli cell tumor in a dog.
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Two large prostatic cysts were found in a dog that had a Sertoli cell tumor in an abdominal testis and other signs of hyperestrogenism, including feminization, dermatologic alterations, and slight anemia. After marsupialization of the cysts and removal of the testes, the clinical signs resolved.
[Immunohistochemical study of Sertoli-stromal cell tumor; comparison between the tumor arising from the gonad of a testicular feminization syndrome bearing patient and from ovaries of non-bearing patients].
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The association of Sertoli-stromal cell tumor with testicular feminization syndrome (TFS) has been elaborated in the past studies. Here, we described immunohistochemical studies on Sertoli cell tumor of the gonad in a TFS patient and compare with 2 other cases of spontaneous ovarian Sertoli-stromal
Genetic engineering to study testicular tumorigenesis.
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In humans, Sertoli cell tumors account for approximately 4% of all testicular tumors, and 20% of these are malignant. The mechanisms underlying Sertoli cell tumorigenesis remain largely unknown. Using gene knockout technology, we previously generated mutant mice lacking the alpha subunit of inhibin
Canine testicular tumors in descended and cryptorchid testes.
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A comparative study of canine testicular tumors in descended and cryptorchid testes was performed in order to associate pathologic features with clinical signs. Observation on 80 canine testicular tumors revealed the following distribution: in undescended testes, 4 tumors were classified as
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