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subarachnoid hemorrhage/hypoxia

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14 risultati

Diet Induced Ketosis for Brain Injury - A Feasibility Study

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Abstract At the Department of Highly Specialized Neurorehabilitation/Traumatic Brain Injury, Rigshospitalet (satellite department at Hvidovre Hospital), approximately 100 patients (pt.) are admitted with severe brain damage every year. From 2015 to 2017, 305 pt. were admitted. Out of the 305 pt.,
Although the brain is only 2% of body weight,it is the most metabolically active and vital organ of the body.Cells in the brain; they need higher amounts of oxygen and energy than other organs in the body. Therefore, in order to maintain brain functions,rich and continuous blood flow and optimal

Cerebral Autoregulation in Patients With Aneurysmal SubArachnoid Haemorrhage

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Spontaneous aneurysm subarachnoid hemorrhage (SAH) occurs annually in approximately 400 people in Denmark. SAH is most commonly seen in younger (median age 56 years) and women (71%), have a high mortality (21-44%) and result in a poor neurological outcome in about 50% of patients. Due to the

Effects of Remote Ischemic Conditioning on Hand Use in Individuals With Spinal Cord Injury

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Most spinal cord injuries (SCI) are not full transections, indicating that there are residual nerve circuits after injury. Rehabilitation interventions after SCI, including physical training and neural stimulation, have been shown to reorganize motor pathways in the brain, corticospinal tract (CST),

Outcome Predictors of Non Traumatic Coma in Children

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Non Traumatic Coma in children is an important pediatric emergency. It has been an enigma for clinicians for many years. To find the cause of coma and to determine the prognosis is a taxing question for the attending clinicians and the primary concern for relatives in every case. Non-traumatic coma

REstricted Versus Liberal Positive End-Expiratory Pressure in Patients Without ARDS

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Research question: Is mechanical ventilation with the lowest possible PEEP level, as compared to mechanical ventilation with the PEEP level currently practiced, non inferior in terms of the number of ventilator-free days at days 28 in patients without ARDS? Study design: National multicenter,

TRansfusion Strategies in Acute Brain INjured Patients

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Although blood transfusions can be lifesaving in severe hemorrhage, they can also have potential complications. As anemia has also been associated with poor outcomes in critically ill patients, determining an optimal transfusion trigger is a real challenge for clinicians. This is even more important

Prolonged Hypoxic Breathing in Healthy Volunteers: a Safety Study

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The primary endpoint of this research study is to prove safety in healthy subjects breathing humidified hypoxic inspiratory gas mixture for 5 days. The secondary endpoint of our study is to describe the physiological and biochemical changes during the 5-day hypoxic period and the 2 days after return

Spreading Depolarization and Ketamine Suppression

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Cortical spreading depolarizations (CSD) are massive events which recently have been observed in many types of acute brain injury and likely lead to expansion of injury. These "brain tsunamis" are unlike any other type of brain electrical event (such as seizures or normal neuronal transmission) in

Changes in Cerebral Oxygenation During the Prone Position in Patients With Acute Respiratory Distress Syndrome

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Primary objectiv Is there a correlation between rSO2 and SpO2 during prone position in patients with ARDS? Inclusion criteria Patient with moderate and severe ARDS from 12h, defined by: - Acute onset of respiratory failure - Parenchymal opacities Bilateral not fully explained by pleural effusion,

Lactate Therapy After Traumatic Brain Injury

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Study: Prospective, single-centre phase II interventional study. The study will take place at the Department of Intensive Care Medicine, Lausanne University Medical Center (Centre Hospitalier Universitaire Vaudois, CHUV), Lausanne, Switzerland. Patient population: Patients will be monitored with an

Admission Bio-clinical Score to Predict One-year Outcomes in Coiled Subarachnoid Hemorrhage (SAH)

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The investigators plan to screen all patients who were consecutively admitted from January 1, 2003 to our neurosurgical intensive care unit after a clinical diagnosis of SAH confirmed by cerebral angiography and treated with a coiling procedure. Patients for whom a decision was made by the treating

Multimodal Resonance Imaging for Outcome Prediction on Coma Patients

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Predicting the awakening of patients in comas is one of the principal stakes of the current neurointensive care unit (neuroICU). Several studies and clinical practice suggest that the multimodal MRI, which associates the traditional morphological sequences (T1, T2*, FLAIR/T2), the spectroscopy-MRI

Erythropoietin Therapy for Subarachnoid Hemorrhage

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BACKGROUND: 1. Delayed ischaemia deficits in subarachnoid haemorrhage Seven thousand patients suffer SAH each year within the UK with young adults (<55 years) being equally affected. Cerebral vasospasm and related cerebral ischemia are the major causes of delayed morbidity and mortality in patients
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