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Pagina 1 a partire dal 264 risultati
Effects of taurine, glycine and GABA on convulsions produced by strychnine in the rabbit.
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The action of intravenously injected taurine, glycine and GABA has been tested on convulsions induced by strychnine using electroencephalographic and electromyographic recordings. The dose of strychnine necessary to produce a generalized tonic-clonic seizure was 0.55 +/- 0.15 mg/kg intravenously for
Effect of taurine on seizures induced by 4-aminopyridine.
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The effect of intraperitoneally injected taurine against the convulsive activity induced by 4-aminopyridine (4-AP) was studied in 12- to 15-day-old mice. At a dose of 2.6 mg/kg, taurine increased the latency of clonic seizures from 7 to 20 minutes, reduced the incidence of tonic seizures from 92% to
Taurine selectivity antagonizes L-kynurenine-produced seizures in mice.
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Taurine in doses of 100 and 200 mg/kg (intraperitoneally) and 2.5 micrograms (into brain ventricles) antagonized clonic seizures produced by L-kynurenine sulfate injected into brain ventricles of SHR adult male albino mice. Seizures produced by another metabolite of tryptophan in the kynurenine
Sodium nitroprusside-induced seizure and taurine release from rat hippocampus.
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We have recently reported that the nitric oxide (NO) donor, sodium nitroprusside (SNP), induces seizures which are associated with an increase in the basal release of aspartate and glutamate from rat hippocampus (Kaku et al., 1998). In order to determine whether taurine release occurs with
[Drug-induced seizures in taurine-deficient mice].
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Appearances of pentetrazole-, picrotoxin- and strychnine-induced convulsive seizures in taurine-deficient mice produced by treatment with guanidinoethyl sulfonate (GES), a taurine transport antagonist, were investigated. Mice were fed a taurine-free diet and water containing 1% GES from 2 weeks of
[Taurine in the cerebrospinal fluid in febrile convulsions in children].
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Taurine may function in brain as a neuroinhibitor, and intracerebroventricular taurine has the capacity to induce hypothermia. Its antiepileptic properties have been observed in animals and humans. On the basis of these data, we studied taurine concentration in the cerebrospinal fluid of 32 children
Levels and uptake of taurine in various brain regions after drug-induced generalized convulsions.
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In a study of the role of taurine in the genesis of epilepsy the effects of metrazol-induced convulsions on the uptake and distribution of taurine in the brain were measured. In vivo we found no significant uptake of taurine in the mouse brain; in rabbit brain in most areas significant taurine
Involvement of taurine in penicillin-induced epilepsy and anti-convulsion of acupuncture: a preliminary report.
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The potential role of taurine on epilepsy and acupuncture anti-convulsion was addressed in the present study. Epilepsy was induced by micro-injection of penicillin into hippocampus of Wistar rats. Taurine was applied by intraperitioneal (i.p.) injection. Electro-acupuncture (EA) was performed on
Seizure-susceptibility and decreased taurine transport in the genetically epileptic rat.
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P(2) fractions from brains of genetically seizure-susceptible (SS) rats as compared to seizure-resistant (SR) rats show decreased high affinity uptake of taurine. Uptakes of GABA and glutamate into P(2) fractions did not differ between the substrains. In neonatal SS rats that had never had a
Higher susceptibility of taurine-deficient rats to seizures induced by 4-aminopyridine.
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The susceptibility of rats made deficient of taurine by treatment with guanidinoethane sulfonate (GES), to seizures induced by 4-aminopyridine was examined. Guanidinoethane sulfonate, at a concentration of 1% was administered to pregnant rats, in the drinking water 2-3 days prior to delivery and the
Effects of intraamygdaloid injection of taurine and valyltaurine on amygdaloid kindled seizure in rats.
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Antiepileptic effects of intracerebral injections of taurine and valyltaurine were examined in amygdaloid kindled rats. The effects were assessed whether the animals can evoke generalized seizures by a 10 microA higher stimulation intensity than triggering thresholds. In all fully-kindled animals
Sulfur - Containing Amino Acids Homocysteine And Taurine In Seizures: Current State Of The Art.
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BACKGROUND
Homocysteine and taurine are non-proteinogenic sulfur-containing amino acids with numerous important physiological roles. Homocysteine and taurine are considered to be neurotransmitters and neuromodulators, the first showing clear hyperexcitability role, while the second is known by its
Effects of taurine on kindled amygdaloid seizures in rats, cats, and photosensitive baboons.
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Acute administration of taurine produced a transient loss of susceptibility to photically induced seizures in photosensitive baboons, but failed to affect kindled amygdaloid convulsions in baboons, rats, and cats. In addition, it was totally ineffective in changing the course of spontaneous status
Lipoic acid effects on glutamate and taurine concentrations in rat hippocampus after pilocarpine-induced seizures.
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Pilocarpine-induced seizures can be mediated by increases in oxidative stress and by cerebral amino acid changes. The present research suggests that antioxidant compounds may afford some level of neuroprotection against the neurotoxicity of seizures in cellular level. The objective of the present
Reduced plasma haptoglobin and urinary taurine in familial seizures identified through the multisib strategy.
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The multisib (MS) sampling strategy was used for detecting possible genetic influences on a complex and heterogeneous disorder. The MS strategy increases the likelihood of selecting pedigrees for single genetic factors and allows the efficient analysis of data. The collection of complete pedigrees
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