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taxol/infiammazione
Il collegamento viene salvato negli appunti
11 risultati
Use of taxol in the treatment of rheumatoid arthritis
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BACKGROUND OF THE INVENTION
This invention is directed to a method of suppression of a progressive, inflammatory, autoimmune arthritis in a mammal, such as rheumatoid arthritis. Despite advances in treatment, arthritis remains an extremely serious health problem, particularly in view of the aging
3-(arylsulfonylamino)-tetrahydropyran-3-carboxylic acid hydroxamides
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BACKGROUND OF THE INVENTION
The present invention relates to 3-(arylsulfonylamino)-tetrahydropyran-3-carboxylic acid hydroxamide derivatives, and to pharmaceutical compositions and methods of treatment of inflammation, cancer as well as other disorders.
The compounds of the present invention are
Gem substituted hydroxamic acids
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BACKGROUND OF THE INVENTION
The present invention relates to geminal disubstituted cyclic hydroxamic acids and derivatives thereof, and to pharmaceutical compositions comprising such derivatives and to the use of such derivatives in the treatment of arthritis, cancer and other diseases. The present
3-(arylsulfonylamino)-tetrahydrofuran-3-carboxylic acid hydroxamides
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BACKGROUND OF THE INVENTION
The present invention relates to 3-(arylsulfonylamino)-tetrahydrofuran-3-carboxylic acid hydroxamide derivatives, and to pharmaceutical compositions and methods of treatment of inflammation, cancer and other disorders.
The compounds of the present invention are inhibitors
Cyclic sulfone derivatives
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BACKGROUND OF THE INVENTION
The present invention relates to cyclic sulfone derivatives which are inhibitors a matrix metalloproteinases or the production of tumor necrosis factor (TNF) and as such are useful in the treatment of a condition selected from the group consisting of arthritis, cancer,
Arylsulfonylamino hydroxamic acid derivatives
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BACKGROUND OF THE INVENTION
The present invention relates to arylsulfonylamino hydroxamic acid derivatives which are inhibitors of matrix metalloproteinases or the production of tumor necrosis factor (TNF) and as such are useful in the treatment of a condition selected from the group consisting of
Arylsulfonylamino hydroxamic acid derivatives
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Entra registrati
The present invention relates to arylsulfonylamino hydroxamic acid derivatives which are inhibitors of matrix metalloproteinases or the production of tumor necrosis factor (TNF) and as such are useful in the treatment of a condition selected from the group consisting of arthritis, cancer, tissue
Arylsulfonyl hydroxamic acid derivatives
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BACKGROUND OF THE INVENTION
The present invention relates to arylsulfonyl hydroxamic acid derivatives which are inhibitors of matrix metalloproteinases or the production of tumor necrosis factor (TNF) and as such are useful in the treatment of a condition selected from the group consisting of
(4-arylsulfonylamino)-tetrahydropyran-4-carboxylic acid hydroxamides
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BACKGROUND OF THE INVENTION
The present invention relates to (4-arylsulfonylamino)-tetrahydropyran-4-carboxylic acid hydroxamide derivatives, and to pharmaceutical compositions and methods of treatment.
The compounds of the present invention are inhibitors of zinc metalloendopeptidases, especially
Phosphinate based inhibitors of matrix metalloproteases
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BACKGROUND OF THE INVENTION
The present invention relates to phosphinate based derivatives which are inhibitors of matrix metalloproteinases or the production of tumor necrosis factor (TNF) and as such are useful in the treatment of a condition selected from the group consisting of arthritis,
Pharmaceutical compositions for the delivery of substantially water-insoluble drugs
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BACKGROUND OF THE INVENTION
1. Field of Invention
This invention relates to compositions and methods useful for the in vivo delivery of substantially water-insoluble drugs, like TAXOL.RTM.. The use of specific composition and preparation conditions enables the reproducible production of unusually
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