Transnasal blockade of SPG approach involving the application of 2 cc (approximately the size of a pea) of 2% lidocaine jelly on a cotton swab directed posteriorly towards the SPG in the nasal passage bilaterally. Cotton swab will be inserted to the back of the nasal passage until it can no longer be inserted any further. The cotton swab should remain in place for 15 minutes on both sides simultaneously. The patient will be instructed on how to perform this procedure on themselves, and they will be given supplies for a 7-day supply of medication to be administered two times per day at approximately 12 hour intervals.

Transnasal blockade of SPG approach involving the application of 2 cc (approximately the size of a pea) of nasal saline jelly on a cotton swab directed posteriorly towards the SPG in the nasal passage bilaterally. Cotton swab will be inserted to the back of the nasal passage until it can no longer be inserted any further. The cotton swab should remain in place for 15 minutes. The patient will be instructed on how to perform this procedure on themselves, and they will be given supplies for a 7-day supply of medication to be administered up to two times per day at approximately 12 hour intervals.

Post-Dural Puncture Headache

Patients will be prescribed a regimen of 1 g acetaminophen q 8hrs alternating with 600 mg ibuprofen q 6 hours. In addition they will be instructed to continue oral fluid hydration and minimal activity for 24 hours.
At 2-hours following the SPG blockade an EBP will be offered to patients. Patient will also be informed that they can request an EBP at any time. The SPG blockade will be performed twice daily in the hospital and twice daily at home, by the patient. The patient will also be informed, if that at anytime, they would like an EBP, it can be provided.
While the study is being conducted, patients will not be offered a SPG block unless enrolled in the study.

Lidocaine HCl Gel 2%

placebo gel

University of Utah

RCT of SPG Blocks for Post-dural Headache

A Multicenter Double Blinded Randomized Controlled Trial of the Efficacy of the Sphenopalatine Ganglion Block for the Treatment of the Postdural Puncture Headache After Labor Epidural

Proportion of postpartum women with a postdural puncture headache (PDPH) requesting epidural blood patch (EBP)

Daily Questionnaire regarding functionality

University of Colorado, Denver

University of California, San Francisco

Duke University

Mayo Clinic

Harvard University

Diabetic Macular Edema

Branch Retinal Vein Occlusion

Chronic Central Serous Retinopathy

Macular Telangiectasia

Topcon Endpoint Management

Instituto de Oftalmologia Lavinsky

Non-damaging Retinal Laser Therapy With PASCAL Laser for Macular Diseases

Phase 2 Study of Non-damaging Retinal Laser Therapy Using PASCAL Laser With Endpoint Management Software for Macular Diseases

Daniel Lavinsky

Professor

Federal University of Rio Grande do Sul

One arm receives laser treatment and second arm received powerless laser treatment as a Sham group.

telangiectasis

febbre

fever

telangiectasis/febbre

RCT of SPG Blocks for Post-dural Headache

Non-damaging Retinal Laser Therapy With PASCAL Laser for Macular Diseases

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