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thapsigargin/cancro
Il collegamento viene salvato negli appunti
5 risultati
Folate-conjugated molecules for delivery of toxic small molecule inhibitors to cancer cells and methods of use
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BACKGROUND
Thapsigargin (TG) is a naturally-occurring compound that is highly specific for inhibiting the sarco/endoplasmic reticulum and endoplasmic reticulum Ca.sup.2+-ATPase pump (SERCA). The inventors recently identified TG as a modulator of Notch (Roti G., et al., "Complementary genomic screens
Tumor treatment method
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FIELD OF THE INVENTION
The present invention relates to a method of treating a solid tumor, and in particular, to a method involving hypoxic stress as one component and protein kinase C activation as another component.
REFERENCES
Cook, P. F., et al., Biochem. 21: 5794-5799 (1982).
Culver, K., et
Reagents and methods for cancer treatment and prevention
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FIELD OF THE INVENTION
The invention generally relates to the treatment of cancer, and, more specifically, to the treatment of tumors, including solid tumors and their metastases, without radiation or standard chemotherapeutic agents. In a preferred embodiment, the invention relates to the
Reagents and methods for cancer treatment and prevention
Solo gli utenti registrati possono tradurre articoli
Entra registrati
FIELD OF THE INVENTION
The invention generally relates to the treatment of cancer, and, more specifically, to the treatment of tumors, including solid tumors and their metastases, without radiation or standard chemotherapeutic agents. In a preferred embodiment, the invention relates to the
Reagents and methods for cancer treatment and prevention
Solo gli utenti registrati possono tradurre articoli
Entra registrati
FIELD OF THE INVENTION
The invention generally relates to the treatment of cancer, and, more specifically, to the treatment of tumors, including solid tumors and their metastases, without radiation or standard chemotherapeutic agents. In a preferred embodiment, the invention relates to the
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