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Pagina 1 a partire dal 103 risultati
Method for regulating cancer stem cell growth by inhibiting phosphorylation of 120th threonine residue of TSPYL5 protein, a composition containing the peptide sequence functioning to inhibit the phosphorylation and a use thereof
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CROSS REFERENCE TO RELATED APPLICATIONS
This is the .sctn. 371 U.S. National Stage of International Application No. PCT/KR2017/006240, filed Jun. 15, 2017, which was published in English under PCT Article 21(2), which in turn claims the benefit of KR Patent Application No. 10-2016-0074655, filed
Regulation of human serine/threonine kinase
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FIELD OF THE INVENTION
The invention relates to the regulation of human serine/threonine kinase.
BACKGROUND OF THE INVENTION
Intercellular signaling regulates a variety of important biological functions. For example, transforming growth factor type beta (TGF-.beta.) regulates the proliferation and
Regulation of human serine-threonine protein kinase
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TECHNICAL FIELD OF THE INVENTION
The invention relates to the area of enzyme regulation. More particularly, the invention relates to the regulation of human serine-threonine protein kinase.
BACKGROUND OF THE INVENTION
Intercellular signaling regulates a variety of important biological functions. For
Regulation of human serine-threonine protein kinase
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TECHNICAL FIELD OF THE INVENTION
The invention relates to the regulation of human serine-threonine protein kinase.
BACKGROUND OF THE INVENTION
Intercellular signaling regulates a variety of important biological functions. For example, transforming growth factor type beta (TGF-.beta.) regulates the
PAK4, a novel gene encoding a serine/threonine kinase
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BACKGROUND OF THE INVENTION
The GTPases Rac and Cdc42Hs control diverse cellular functions. In addition to being mediators of intracellular signaling cascades, they have important roles in cell morphogenesis and mitogenesis. A novel PAK related kinase, PAK4, has been identified as a new effector
PAK4, a novel gene encoding a serine/threonine kinase
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Throughout this application, various references are referred to within parentheses. Disclosures of these publications in their entireties are hereby incorporated by reference into this application to more fully describe the state of the art to which this invention pertains. Full bibliographic
Regulation of human wee1-like serine/threonine protein kinase
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TECHNICAL FIELD OF THE INVENTION
The invention relates to the regulation of human WEE1-like serine/threonine protein kinase.
BACKGROUND OF THE INVENTION
Protein tyrosine kinases catalyze the following reaction: ATP+protein tyrosine=ADP+protein tyrosine phosphate. Because of the importance of this
P13K pathway mutations in cancer
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TECHNICAL FIELD OF THE INVENTION
This invention is related to the area of anti-cancer therapeutics and drug discovery. In particular, it relates to identification of targets suitable for development of specific therapies and to stratification of patients based on status of these targets.
BACKGROUND
AKT inhibitor compounds for treatment of cancer
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RELATED APPLICATIONS
This application is a 35 U.S.C. .sctn.371 filing of International Application No. PCT/GB2013/050771, filed Mar. 25, 2013, which claims priority to Great Britain Application No. 1205164.5, filed Mar. 23, 2012, each of which is incorporated herein by reference in its entirety.
The
Method for discriminating between prostate cancer and a benign prostate disease
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TECHNICAL FIELD
The present invention relates to a method of analyzing diagnostic information pertaining to a benign prostate disease and prostate cancer. The present invention also relates to a method of analyzing diagnostic information based on the blood concentration of mucin-1 having a specific
Reagents, methods, and test kit for diagnosing/monitoring cancer in humans
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DESCRIPTION
1. Technical Field
The invention is in the field of cancer diagnosis and monitoring. More particularly it concerns a method for diagnosing cancer or monitoring the status of cancer in patients already diagnosed as having cancer by determining the amount of N-[9(.beta.-D-ribofuranosyl)
Methods and test kit for diagnosing/monitoring cancer in humans
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DESCRIPTION
1. Technical Field
The invention is in the field of cancer diagnosis and monitoring. More particularly it concerns a method for diagnosing cancer or monitoring the status of cancer in patients already diagnosed as having cancer by determining the amount of certain modified nucleosides in
STK32C gene relevant to breast cancer and use thereof
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CROSS-REFERENCE TO RELATED APPLICATIONS
This application is the U.S. national phase application filed under 35 U.S.C. .sctn. 371 claiming benefit to PCT International Application No. PCT/KR2016/009134, filed on Aug. 19, 2016, which claims priority to Korean Patent Application Serial No.
Method for determination of prognosis of prostate cancer, and diagnostic agent for use in the method
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TECHNICAL FIELD
The present invention relates to a method for determining probability that a prostate cancer will metastasize, and to a diagnostic reagent therefor.
BACKGROUND ART
In the U.S., prostate cancer has the highest prevalence among cancers in males. In Japan too, the prevalence of the
Method of using beta-hydroxy-beta-methylbutyrate for reducing tumor growth rate
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The present invention relates to methods for the prevention and treatment of chronic inflammatory diseases, cancer, and involuntary weight loss. In the practice of the present invention patients are enterally administered HMB alone or alternatively in combination with eicosapentaenoic (20:5
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