PCOS

Astaxanthin 4 mg

placebo

The Effect of Astaxanthin on Hormonal Parameters and Oxidative Stress Indices in Patients With Polycystic Ovary Syndrome

The Effect of Astaxanthin on Hormonal Parameters and Oxidative Stress Indices in Serum, and Induction of Signaling Pathways in Granulosa Cells in Patients With Polycystic Ovary Syndrome

This parameter will measure using Enzyme-Linked. Immunosorbent Assays (ELISAs)

Tehran University of Medical Sciences

Patients will be asked to consume 1 pill daily with a meal, for six months. The pills will contain 22 mg total of the carotenoids lutein (10 mg), zeaxanthin (2 mg), and mesozeaxanthin (10 mg).

Patients will be asked to consume 1 pill daily with a meal, for six months. The pills will contain only sunflower oil (placebo).

Glaucoma

The intervention will involve supplementation with the macular carotenoids (1 pill daily with a meal containing lutein, zeaxanthin, mesozeaxanthin) for six months, to determine the effects on visual performance in glaucoma patients.

Lutein, zeaxanthin and mesozeaxanthin

This intervention involves an inert pill (1 pill daily with a meal) that contains only sunflower oil, for six months.

Placebo

Duke University Eye Center

Macular Pigment and Visual Performance in Glaucoma Patients

Ability of the patient to discern faint borders that mark the boundary between relatively dark and light areas

Accumulation of the macular carotenoids (lutein, zeaxanthin, and mesozeaxanthin) occurs in the central retina, and is characterized by its optical density (the ability of the pigment to absorb light).

After exposure to a relatively bright environment, visual adaptation to the dark (where one can reliably detect objects in dim light) takes some time.

Visual performance, especially contrast sensitivity, is greatly decreased by the presence of glare.

The NEI VFQ-25 is a 25-question visual function quality questionnaire. Values are assigned from 0 to 100 according to the answers to 25 items. Higher values represent a better outcome.

A visual field assessment tests the sensitivity of regions across the retina that correspond to points in the visual field.

The point-spread function describes the optical quality of the eye.

Felipe Medeiros, MD

Professor of Ophthalmology

Heidelberg Engineering GmbH

MacuHealth LP

Industrial Orgánica S.A. de C.V.

oral administration of 0.28 mg of lutein in two doses: within 6 hours (hrs) after birth and at 36 hrs of life

oral administration of 0.28 mg of vehicle (0.5 mL of 5% glucose solution) in two doses: within 6 hours (hrs) after birth and at 36 hrs of life

Infant, Newborn, Diseases

Other Lipid Storage Disorders

After randomisation, the infant received orally a total dose of 0.28 mg of lutein in two doses: within 6 hours after birth and at 36 hours of life

Lutein drops

After randomization, newborns received 0.5 mL of 5% glucose solution in two doses: within 6 hours (hrs) after birth and at 36 hrs of life.

Glucose drops

AOUS

Evaluation of Antioxidant Activity of Oral Lutein in Preterm and Term Newborn

Giuseppe Buonocore

Professor

University of Siena

Careggi Hospital

Participants who were enrolled in the AREDS or AREDS2 protocol and successfully completed the final AREDS or AREDS2 follow-up visit.

Age-Related Macular Degeneration

Cataract

National Institutes of Health Clinical Center, 9000 Rockville Pike

Age-Related Eye Disease Study (AREDS) Follow-Up

Age-Related Eye Disease Study (AREDS) and AREDS2 Follow-Up

Data on possible ocular events for both AMD and cataracts and for document of any adverse effects associated with the AREDS treatment.

xanthophyll/infiammazione

The Effect of Astaxanthin on Hormonal Parameters and Oxidative Stress Indices in Patients With Polycystic Ovary Syndrome

Macular Pigment and Visual Performance in Glaucoma Patients

Evaluation of Antioxidant Activity of Oral Lutein in Preterm and Term Newborn

Age-Related Eye Disease Study (AREDS) Follow-Up

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