[Isolation and elucidation of antioxidant constituents from acetone extract in root of Scutellaria rehderiana].

OBJECTIVE

To isolatate and elucidate the antioxidant constituents from acetone extract of Scutellaria rehderiana.

METHODS

Chemical constituents were isolated by several column chromatographies and their structures were elucidated on the basis of standard compounds and spectral analysis.

RESULTS

Five compounds, oroxylin A, wogonin, baicalein, ganhuangenin, ganhuangemin were isolated from acetone extract of S. rehderiana. Baicalin was obtained from methanol extract of S. rehderiana.

CONCLUSIONS

Ganhuangemin was isolated from the plant for the first time. Baicalein and ganhuangenin have stronger antioxidant activity than that of BHT (butylated hydroxytoluene).