Pharmacological investigations of volatile oil of cyperus eleusinoides kunth effect on central nervous system.

Volatile oil exhibited depressant effect on central nervous system of rats and mice. It blocked CAR in 80% animals and potentiated effects of chlorpromazine hydrochloride on CAR and pentobarbitone induced hypnosis in mice. It exhibited hypothermic and analgesic activities and potentiated morphine induced analgesia considerably. The volatile oil checked tonichind limb extension produced by electric shocks but failed to check strychnine and mentrazol induced convulsions The antipyretic activity of the volatile oil was not significant.