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A low glycemic index diet (LGIT) is a modification of a ketogenic diet (KD) that includes low carbohydrate, medium protein, and high fat intake.It is a potential new intervention for refractory schizophrenia.The possible mechanism is that relatively low and stable blood sugar levels trigger the
The prevalence of xerostomia varies high in patients with chronic hemodialysis (HD), and the decreased saliva flow rate due to various mechanisms is the main factor in its development. The significant decrease in saliva flow due to the atrophy and fibrosis of the salivary glands in HD patients is
Study design: This study is designed as a randomized, double-blind, placebo-controlled, clinical multi-centre trial. Its main objective is to evaluate the efficacy of SFN vs placebo in decreasing risk and conversion rate of psychosis in CHR population. A total of 300 CHR subjects will be recruited
Parkinson's disease (PD) is a neurodegenerative condition which has a 1% prevalence in the over 60s and also affects young adults. As well as motor symptoms such as akinesia or rigidity, many patients also experience non-motor symptoms of which psychosis is the most common (Chang and Fox, 2016).
Background:
The Italian document Stato Regioni (an agreement between Italian Government and local regions) analyses objectives indicated by the PANSM (Piano Nazionale di Azioni per la Salute mentale - National Plan of Actions for Mental Health) to identify pathways of care for severe mental
Variable: History of Fall (HoF) A fall can be defined as "an unexpected event in which the participant comes to rest on the ground, floor, or lower level" and "excludes coming to rest against furniture, wall, or other structure" .
The HoF within the previous 12 months will be determined by
Bruxism is different from temporomandibular joint disease because of long periods of muscle contraction. It is considered an eloquent contributory factor in the etiology of temporomandibular disorders (TMD). The incidence of bruxism is estimated to be approximately between 5% and 10% of the adult
Summary Melatonin is a naturally produced hormone involved in the synchronization of circadian rhythms and the sleep-wake cycle in humans. It is often given as a sleep aid and is generally well tolerated, with very few drug-drug interactions. Recent studies have shown marginal benefit in increasing
In the current study, the investigators aim to investigate the effect of additional treatment with prednisolone on symptomatic improvement, global functioning, cognition and on immunological parameters in patients with early-stage psychotic disorder, applying a randomized double-blind
This is a pilot single-center prospective cohort. After inclusion, patients status (including magnesium levels) will be evaluated (1 and 3 months of treatment) and that status will define the exposure criterion. Included patients will be followed for 1 year during which cardiometabolic markers will
The study treatment sequence involves three stages, which are referred to as steps:
Step 1- Support and Problem Solving (SPS)
All trial participants receive SPS treatment in Step 1. Step 1 involves attending weekly-fortnightly SPS sessions over a six week period and the Week 4 and 6 visits will also
Primary objective
To assess the feasibility of recruiting both community and in-patients from different centres. Specifically, the feasibility study will:
1. Ascertain whether the study design is acceptable to participants, including randomisation and use of telephone interviews.
2. Ascertain
Background Tourette's syndrome (TS) is characterized by the occurrence, before 18 years of age, of multiple motor and vocal tics, which do not necessarily occur concomitantly. Tics constitute the clinical hallmark of TS; they are sudden, brief, intermittent involuntary (or semi-involuntary)
Alzheimer's disease (AD) is a progressive type of dementia that causes problems with memory, thinking and behavior that gradually worsen over time. With an aging population, AD is an escalating problem, currently affecting an estimated 35 million people worldwide, with this number expected to grow
Parallel-group, double blind (evaluation and analysis), randomized clinical trial (pilot study). The design was based on recommendations for conducting pilot studies (Thabane 2010).
The main objective of the MID-Nurse (Randomized Clinical Trial) was to analyze if a multicomponent nurse-led