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artesunate/עששת

הקישור נשמר בלוח
מאמריםניסויים קלינייםפטנטים
8 תוצאות

Effect of artesunate on Toxoplasma gondii: in vitro and in vivo studies.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
The effect of Artesunate (As) on Toxoplasma gondii (T. gondii) in vitro and in vivo was studied. In vitro, tachyzoites of RH strain were exposed to As in a concentration of 2 microg/ml for 72 hours. The assessment of As effect was carried out by studying the viability, infectivity and ultrastructure

Preparation and characterization of a novel host-guest complex based on folate-modified β-cyclodextrin and artesunate.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
The purpose of this study was to develop a novel folate-modified host-guest complex to enhance antitumor activity of the artesunate and improve the solubility and stability by encapsulated in β-cyclodextrin and linked with folate. In this work, we designed and prepared the inclusion complex of

The anti-malaria agent artesunate exhibits cytotoxic effects in primary effusion lymphoma

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Primary effusion lymphoma (PEL), caused by Kaposi's sarcoma-associated herpesvirus (KSHV), presents as a lymphomatous effusion in body cavities and has a poor prognosis. The anti-malaria drug, artesunate, possesses anti-neoplastic potential. Therefore, we aimed to investigate its effect on

[Effect of artesunate on the transplantation tumor of parotid gland in the nude mice with adenoid cystic carcinoma drug resistance cell].

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Objective:To observe the effect of Artesunate on the transplantation tumor of parotid gland in the nude mice with adenoid cystic carcinoma drug resistance cell and to explore its clinical application prospect as an anticancer drug.Method:Twenty male BALB/C mice were chose to set up parotid gland
Inclusion of artesunate in the cavity of β-cyclodextrin (β-CD) as well as its methyl and hydroxypropyl derivatives was investigated experimentally and by molecular modeling studies. The effect of PEG on the inclusion was also studied. A 1:1 stoichiometry was indicated by phase-solubility studies
Reactive oxygen species (ROS)-mediated apoptosis is considered a crucial therapeutic mechanisms for artesunate (AS). As an Fe(II)-dependent drug, the anticancer effect of AS is often limited due to insufficient Fe(II) concentration in targeted cells. To overcome this problem, a recombinant

[Malaria in Vietnam. Environment, prevention and treatment].

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
In Viet-nam, malaria rages in mountainous and wooded areas, as well as in coastal areas. In these geographical zones, the diversified features of environment have different repercussions on the development of Anopheles species. The main vector species have strict oecological requirements: An. dirus,

Interaction of artemisinin and its derivatives with human serum albumin studied using spectroscopies and molecular modeling methods.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
The interactions of artemisinins including artemisinin, dihydroartemisinin, artemether and artesunate with human serum albumin (HSA) were studied by fluorescence spectroscopy, UV-Vis absorption spectroscopy, synchronous fluorescence, three-dimensional fluorescence, circular dichroism (CD) and
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