Novel retro-anandamides are presented which have high affinities for the cannabinoid CB1 and/or CB2 receptor sites. Further, most of the analogs exhibit greater metabolic stability than arachidonylethanolamide. The improved receptor affinity and selectivity and/or greater metabolic stability make these analogs therapeutically useful as medications in individuals and animals for treatment of pain, glaucoma, epilepsy, nausea associated with chemotherapy, as well as suppression of the immune system, enhancement of appetite and in treatment of certain mental disorders.

University of Connecticut

Retro-anandamides, high affinity and stability cannabinoid receptor ligands

Novel polycyclic cannabinoid analogs are presented which have preferentially high affinities for the cannabinoid CB2 receptor sites. The improved receptor affinity makes these analogs therapeutically useful as medications in individuals and animals for treatment of pain, glaucoma, epilepsy, nausea associated with chemotherapy.

Bicyclic cannabinoid agonists for the cannabinoid receptor

A method for treating radiotherapy- or chemotherapy-induced cognitive or emotional impairment by topically administering a cannabinoid. Also provided is a method for treating a tumor by topically administering a cannabinoid together with radiotherapy and/or chemotherapy.

chemotherapy/קנאביס

Retro-anandamides, high affinity and stability cannabinoid receptor ligands

Bicyclic cannabinoid agonists for the cannabinoid receptor

Bicyclic cannabinoid agonists for the cannabinoid receptor

Method for treating tumors with cannabinoids

המאגר השלם ביותר של צמחי מרפא המגובה על ידי המדע