coumarin/נקרוזה

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מאמריםניסויים קלינייםפטנטים

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עמוד 1 מ 297 תוצאות

Skin necrosis following prolonged administration of coumarin in a patient with inherited protein S deficiency.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Depression of the vitamin K-dependent modulators of coagulation during the initial phase of oral anticoagulant therapy may lead to a transient hypercoagulable state and skin necrosis. We report a case of skin necrosis associated with inherited protein S deficiency following prolonged coumarin

Successful administration of low molecular weight heparin in a patient with heparin-induced thrombocytopenia and coumarin-induced skin necrosis.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

A case of heparin-induced thrombocytopenia and skin necrosis induced by coumarin is reported in a 58-year-old female patient suffering from metastatic breast adenocarcinoma and deep vein thrombosis. The thrombosis resolved after treatment with low molecular weight heparin and the thrombocytopenia

Coumarin necrosis, neonatal purpura fulminans, and protein C deficiency.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Protein C (PC), a 62,000-molecular weight vitamin K-dependent serine protease zymogen, is a natural anticoagulant that occurs in plasma at 4 mg/L. Activated PC inactivates clotting factors V and VIII and is also profibrinolytic. Activated PC is enhanced in its anticoagulant activity by protein S

Coumarin necrosis.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Necrosis of the skin developed soon after the initiation of coumarin therapy in an elderly woman. Inadvertent rechallenge resulted in similar lesions. Coumarin necrosis is a poorly understood phenomenon unlikely to respond to therapy. Fortunately, its incidence is quite rare, considering the

Coumarin necrosis of the penis.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Coumarin-induced necrosis of the skin and subcutaneous tissue is an uncommon but well recognized complication of anticoagulant therapy. Although any area of skin may be involved necrosis of the penis is rare. We report a case of penile necrosis associated with coumarin therapy and review the

Heterozygous protein C deficiency and coumarin necrosis of the skin.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

An obese female patient aged 47 with a personal and familial history of recurrent venous thrombosis, who developed a coumarin-induced skin necrosis is presented. Laboratory investigations, performed three months after the acute event and in absence of coumarin therapy, emphasized a decreased

A case of coumarin necrosis with penile and pedal involvement.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

A 57-year-old male patient with advanced adenocarcinoma of the lung, who was administered oral anticoagulant therapy because of pulmonary embolism, developed coumarin necrosis confined to the penis and feet. To our knowledge, this patient showing acral involvement is the seventh case of

[Coumarin-induced necrosis--a rare complication of oral anticoagulant therapy].

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Coumarin-induced skin necrosis represents a clinical entity that occurs very rarely, with an approximate incidence of 0.01-0.1% at patients following oral anticoagulant therapy. Most of the cases become clinical manifest between the 3rd and 6th of anticoagulant treatment (there were reports of late

Coumarin-induced skin necrosis. Incidence, mechanisms, management and avoidance.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Coumarin-induced tissue necrosis is a complication of oral anticoagulant therapy characterised by necrosis of the skin and underlying tissue. This occurrence of microvascular thrombosis associated with the administration of an anticoagulant has perplexed the medical and pharmaceutical community

Recurrent coumarin-induced skin necrosis in a patient with an acquired functional protein C deficiency.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

An elderly woman who had been receiving long-term oral anticoagulant therapy developed skin and subcutaneous fat necrosis on five repeated occasions of extreme hypocoagulability, associated with coinciding periods of congestive cardiac failure. In each episode, the skin necrosis developed within

Deep-vein thrombosis and coumarin skin necrosis associated with a factor V inhibitor with lupus-like features.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

We report a 71-year-old man who developed deep-vein thrombosis after major surgery. Coumarin skin necrosis developed after starting oral anticoagulant therapy. An inhibitor to factor V (61 Bethesda units) with lupus-like features was found as well as a low protein C level. The occurrence of these

Successful prevention of coumarin-induced hemorrhagic skin necrosis by timely administration of vitamin k1.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Successful prevention of the progression of incipient hemorrhagic skin necrosis by timely administration of vitamin K1 in a woman treated with phenprocoumon is presented. From a critical review of the literature strong evidence emerges that coumarin necrosis does only occur in cases with severe

Repeated occurrence of skin necrosis twice following coumarin intake and subsequently during decrease of vitamin K dependent coagulation factors associated with cholestasis.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

A female patient is described who developed skin and subcutaneous fat necrosis on two occasions after intake of acenocoumarol. Several months later identical skin changes occurred during an episode of cholestasis associated with a prolongation of the prothrombin time to an extent comparable with

Coumarin skin necrosis in a patient with heparin-induced thrombocytopenia--a case report.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

A patient with evidence of both heparin-related thrombocytopenia and coumarin-induced skin necrosis is presented. Etiology, diagnostic evaluation, histopathology, and therapeutic options are discussed.

Skin necrosis, a rare complication of coumarin therapy.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Coumarin congeners are frequently being prescribed in vascular surgery. The complication most often seen in haemorrhage. A less known complication is necrosis of skin and soft tissues. This rare complication is potentially lethal. The etiology is unclear, a relation with protein C deficiency seems

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