Achalasia

Pt. are going to submit a POEM procedure.

POEM

Istituto Clinico Humanitas

Risk of Microbial Translocation in Patients Undergoing Per-Oral Endoscopic Myotomy (POEM) for Achalasia: Antibiotic Prophylaxis or Short-therapy

Assesment of fever (TC>38°C) and systemic inflammation (increased in white blood cells (WBC) and/or protein C-reactive (PCR)) that may occur following POEM

Topical PRK 124 (Pyratine-6)(0.125%) moisturizing lotion applied twice daily to the face for 48 weeks. Subjects will wash their faces prior to application. The applications will occur in the mornings and one hour before bedtime.

Topical PRK 124

Sex: Female, Male

Region of Enrollment

Measured by percent improvement on a scale of 0-4. Subjects received a 0 for no improvement, 1 for less than twenty-five percent improvement, a 2 for twenty-five to fifty percent improvement, a 3 for fifty to seventy-five percent improvement and a 4 for greater than seventy-five percent improvement. Mean scores from all continuing 16 participants were averaged for each encounter, for a total of 8 visits. The percent improvement in mean erythema severity was calculated by comparing the change in mean scores at week 48 to mean scores assessed at baseline.

Erythema Severity

Skin Tolerance

Skin Photodamage

Transepidermal Water Loss (TEWL)

Cosmetic Acceptability

Lesion counts were numerically summed for each patient at each encounter, and the average lesion count was calculated from all continuing 16 subjects at each visit, for a total of 8 visits. Percent improvement (reduction in lesion number) was assessed by comparing the average number of lesions at week 48 to the average number of lesions assessed at baseline.

Inflammatory Lesion Count

Measured by percent improvement on a scale of 0-4. Subjects received a 0 for no improvement, 1 for less than twenty-five percent improvement, a 2 for twenty-five to fifty percent improvement, a 3 for fifty to seventy-five percent improvement and a 4 for greater than seventy-five percent improvement. Mean scores from all continuing 16 participants were averaged for each encounter, for a total of 8 visits. The percent improvement in mean telangiectasia severity was calculated by comparing the change in mean scores at week 48 to mean scores assessed at baseline.

Telangiectasia Severity

Overall Study

Brian Swasdibutra, Clinical Research Coordinator

Acne Rosacea

Topical PRK 124 (0.125%) moisturizing lotion applied twice daily to the face for 48 weeks

PRK 124

UC Irvine Dermatology Clinical Research Center

Effects of PRK 124 Lotion in Acne Rosacea

Effects of PRK 124 (0.125%) Lotion in Acne Rosacea

Christopher Zachary

MBBS, FRCP

University of California, Irvine

SenetekPLC

Schizophrenia

Shiatsu treatment provided in 40-minute sessions, twice a week for 4 weeks

cytokinin/דלקת

Risk of Microbial Translocation in Patients Undergoing Per-Oral Endoscopic Myotomy (POEM) for Achalasia: Antibiotic Prophylaxis or Short-therapy

Effects of PRK 124 Lotion in Acne Rosacea

Shiatsu Adjuvant Therapy For Schizophrenia

המאגר השלם ביותר של צמחי מרפא המגובה על ידי המדע