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Metabolic symbiosis in cancer: refocusing the Warburg lens.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Using relatively primitive tools in the 1920s, Otto Warburg demonstrated that tumor cells show an increased dependence on glycolysis to meet their energy needs, regardless of whether they were well-oxygenated or not. High rates of glucose uptake, fueling glycolysis, are now used clinically to

Viewing Siglecs through the lens of tumor immunology.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Many Siglecs function as inhibitory receptors on innate and adaptive immune cells and may contribute to the attenuation of immune responses to tumors. Siglec 9 on neutrophils and Siglec 7 on NK cells are prominent examples of inhibitory Siglecs that can potentially dampen anti-tumor immunity. CD169

Lens opacification and H2O2 elevation induced by a tumor promoter.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Incubation of whole bovine lens with 10(-7) M 12-O-tetradecanoylphorbol-13-acetate (TPA) led to the lens opacity within 24 h. The hydrogen peroxide (H2O2) concentration in the whole lens was elevated 4 fold after treatment with either 10(-7) M TPA or 2.5 mM glucose/20 microM glucose oxidase. The

Design of tapered arm impulse radiating antenna with log periodic lens system for skin cancer treatment.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

A Prolate-Spheroidal Impulse Radiating Antenna (PSIRA) is used as a non-invasive technique for generating an electromagnetic implosion to kill melanoma cells. It can launch and focus fast (100 ps) high voltage (>50 KV) pulses into the biological targets. It can be used to obtain electromagnetic

Enhanced depletion of lens reduced glutathione Adriamycin in riboflavin-deficient rats.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

The anticancer drug Adriamycin has photosensitizing properties which potentially may be detrimental to lens tissue. Since reduced glutathione (GSH) serves to protect lens from photo-oxidative stress and dietary riboflavin is required by glutathione reductase to regenerate GSH, we investigated

Cataract Surgery with Primary Lens Implantation in Children with Chronic Uveitis.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

OBJECTIVE To evaluate the evolution of chronic uveitis in children undergoing cataract surgery with primary intraocular lens (IOL) implantation. METHODS Twelve children with chronic uveitis underwent cataract surgery with primary posterior chamber intraocular lens (IOL)

Generation and control of sound bullets with a nonlinear acoustic lens.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Acoustic lenses are employed in a variety of applications, from biomedical imaging and surgery to defense systems and damage detection in materials. Focused acoustic signals, for example, enable ultrasonic transducers to image the interior of the human body. Currently however the performance of

Design of PSIRA with focusing lens concentrating picosecond impulse on biological target.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

The Prolate Spheroidal Impulse Radiating Antenna (PSIRA) is used to radiate very fast pulses in a narrow beam with low dispersion and high field amplitude. The PSIRA is suitable to apply fast, intense pulses without direct contact, for skin cancer treatment. In this proposed work, SWB (Slanted Wire

Fluorescence study on the interaction between hypericin and lens protein "alpha-crystallin".

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Hypericin has been reported as a potent photosensitizing agent exhibiting antiviral, antibacterial, antineoplastic activities. Although its photophysics and mode of action are strongly modulated by the binding protein, detailed information about its mechanism of interaction with possible cellular

Timing of cisplatin administration for chemoradiotherapy in transgenic mice bearing lens tumors.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Cisplatin-based concurrent chemoradiotherapy (CCRT) has become a standard treatment for cancer of the uterine cervix. However, there have been no investigations into the optimum timing for administration of anticancer drugs using animal models. The aim of the present study was to determine the

Anti-tumor Drug THZ1 Suppresses TGFβ2-mediated EMT in Lens Epithelial Cells via Notch and TGFβ/Smad Signaling Pathway.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Selective covalent CDK7 inhibitor THZ1 is a promising potential anti-tumor drug in many kinds of cancers. Epithelial-mesenchymal Transition (EMT) is highly related to cancer initiation, development, invasion and metastasis and other pathogenesis processes. We treated cancer cell line Hela229 and

The antitumor drug 3-nitrobenzothiazolo(3,2-a)quinolinium chloride (NBQ): effects on lens regeneration and interaction with DNA of Notophthalmus viridescens.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

We have studied the effect of 3-nitrobenzothiazolo(3,2-a)quinolinium (NBQ) on the regeneration of the lens in adult newt Notophthalmus viridescens. NBQ has marked cytotoxic effects in tumor cells, intercalates DNA, and was found to enhance lens regeneration. Newt liver DNA was isolated, and the

Zinc oxide nanoparticles inhibit Ca2+-ATPase expression in human lens epithelial cells under UVB irradiation.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Epidemiological and experimental studies have revealed that lens epithelial cells exposed to ultraviolet B (UVB) light could be induced apoptosis, and lens epithelial cell apoptosis can initiate cataractogenesis. Posterior capsular opacification (PCO), the most frequent complication after cataract

Tracking the evolution of cancer cell populations through the mathematical lens of phenotype-structured equations.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

A thorough understanding of the ecological and evolutionary mechanisms that drive the phenotypic evolution of neoplastic cells is a timely and key challenge for the cancer research community. In this respect, mathematical modelling can complement experimental cancer research by offering alternative

Looking Through the Lens of a Family Planner to Prioritize Reproductive Health Among Women With Cancer.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Prioritization of cancer treatment initiation in women of reproductive age may underscore potential implications on reproductive health. This study describes a family planning quotient (FPQ) and reproductive life index (RepLI) tool designed to help providers to discuss effectively

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