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Glutathione: a vital lens antioxidant.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

The reducing compound glutathione (GSH) exists in an unusually high concentration in the lens where it functions as an essential antioxidant vital for maintenance of the tissue's transparency. In conjunction with an active glutathione redox cycle located in the lens epithelium and superficial

Lens glutathione, lens protein glycation and electrophoretic patterns of lens proteins in STZ induced diabetic rats.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

As diabetes is a very complex disease, with the pathological symptoms varying with age, diabetic type and means of control, it still warrants many in vivo and in vitro studies. During hyperglycaemia, increases in the sorbitol pathway, nonenzymatic glycosylation of lens proteins and damage to

Preventive role of lens antioxidant defense mechanism against riboflavin-mediated sunlight damaging of lens crystallins.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

The main components of sunlight reaching the eye lens are UVA and visible light exerting their photo-damaging effects indirectly by the aid of endogenous photosensitizer molecules such as riboflavin (RF). In this study, lens proteins solutions were incubated with RF and exposed to the sunlight.

Lens-induced uveitis.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

has been described in humans and many animal species. Traumatic rupture of the lens capsule may result in vision-threatening intraocular inflammation that is poorly responsive to medical management. Phthisis bulbi, persistent uveitis or glaucoma often occurs in these eyes. Surgical removal of the

Lens UVA photobiology.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Although UVA radiation was considered to be benign as a factor that could contribute to cataract formation, the studies briefly summarized herein show that UVA may provide the more damaging radiant energy involved in the formation of human cataract. Of the UVA impinging onto the eye from sunlight, a

Is the lens canned?

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

The ocular lens somehow remains pellucid despite bombardment by ultraviolet radiation and endogenous hydrogen peroxide (present in the humoral fluids which bathe this tissue). The lens and adjacent aqueous and vitreous humors contain exceptionally high concentrations of reducing substances,

Glutathione levels of the human crystalline lens in aging and its antioxidant effect against the oxidation of lens proteins.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

This paper reports the role of glutathione (GSH) in the crystalline lens as an antioxidant against the oxidation of lens protein. GSH levels in normal lenses decreased gradually with increasing age, from approximately 5 mumol per g lens (wet weight) to 3 mumol per g lens (wet weight). On the other

Effects of different antioxidants on lens-induced uveitis.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

For evaluation of the effects of different free-radical scavengers on biochemical changes in lens-induced uveitis (LIU), ten male Wistar rats were sensitized for 8 weeks using bovine lens protein and Freund's adjuvant. The uveitis was induced by disruption of the lens capsule. One group of animals

Cholesterol may act as an antioxidant in lens membranes.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

OBJECTIVE Oxidative damage has been considered as a major factor involved in cataract formation. We have recently shown that cholesterol oxides accumulate in human cataractous lenses. The biological significance of accumulation of oxysterols in the lens is still poorly understood. However, it has

Ovothiol A is the Main Antioxidant in Fish Lens.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Tissue protection from oxidative stress by antioxidants is of vital importance for cellular metabolism. The lens mostly consists of fiber cells lacking nuclei and organelles, having minimal metabolic activity; therefore, the defense of the lens tissue from the oxidative stress strongly relies on

TAT-mediated PRDX6 protein transduction protects against eye lens epithelial cell death and delays lens opacity.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

A diminished level of endogenous antioxidant in cells/tissues is associated with reduced resistance to oxidative stress. Peroxiredoxin 6 (PRDX6), a protective molecule, regulates gene expression/function by controlling reactive oxygen species (ROS) levels. Using PRDX6 protein linked to TAT, the

Ascorbic acid and the eye lens.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Exposure of mice to hyperbaric oxygen leads to an inhibition of the mitotic activity in the germinative epithelium of the lens. This is followed by an eventual development of cataracts. Cataracts have also been observed in human beings treated with hyperbaric oxygen for different afflictions. The

The structural damages of lens crystallins induced by peroxynitrite and methylglyoxal, two causative players in diabetic complications and preventive role of lens antioxidant components.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Peroxynitrite (PON) and methylglyoxal (MGO), two diabetes-associated compounds, are believed to be important causative players in development of diabetic cataracts. In the current study, different spectroscopic methods, gel electrophoresis, lens culture and microscopic assessments were applied to

Antioxidant status in persons with and without senile lens changes.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Biochemical evidence on lens culture suggests that antioxidant nutrients can protect lens against peroxidation caused by radiation. A case-control study was carried out on 262 middle aged (45-54) and aged (55-64) subjects. The relationship between biochemical markers of antioxidant status and senile

Antioxidant status of dog aqueous humor after extracapsular lens extraction.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

We determined the antioxidant status of the aqueous humor after extracapsular lens extraction in 14 mongrel dogs weighing about 10 kg. The animals were examined by slit lamp biomicroscopy, applanation tonometry and indirect ophthalmoscopy. One eye was submitted to conventional extracapsular lens

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