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mannan/סרקומה

הקישור נשמר בלוח
מאמריםניסויים קלינייםפטנטים
15 תוצאות
The D-mannan of Saccharomyces cerevisiae X2180-1A-5 mutant strain, which possesses a main chain composed of alpha-(1 yields 6) linked D-mannopyranosyl residues and a small proportion of branches composed of alpha-(1 yields 2)- and alpha-(1 yields 3)-linked D-mannopyranosyl residues, showed strong

Antitumor activity of acidic mannan fraction from bakers' yeast.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
The acidic fraction of bakers' yeast mannan containing mannose (93.6%), nitrogen (1.0%), and phosphorus (0.6%), designated as WAM025, showed a marked antitumor activity against the ascites forms of Ehrlich, sarcoma 180 and Meth A tumors in vivo. Namely, a 100% survival of mice transplanted with

Decreased mortality of Norman murine sarcoma in mice treated with the immunomodulator, Acemannan.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
An extract from the parenchyma of Aloe barbadensis Miller shown to contain long chain polydispersed beta (1,4)-linked mannan polymers with random O-acetyl groups (acemannan, Carrisyn) was found to initiate the phagocyte production of monokines that supported antibody dependent cellular cytotoxicity
Three clones of myeloproliferative virus (MPV)-transformed rat fibroblasts (NRK) with different growth properties and morphology were transplanted to athymic nude mice. Presence of carbohydrate-binding proteins was inferred by fluorescence microscopy using fluorescent, glycosylated markers. Salt and
To elicit specific cellular immune responses against cancer, the development of efficient devices to deliver tumor antigen peptides to the MHC class I pathway constitutes a central issue. We report here a novel formula of hydrophobized polysaccharide nanoparticles, which can deliver a HER2

Human herpesvirus 8 infects and replicates in primary cultures of activated B lymphocytes through DC-SIGN.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Human herpesvirus 8 (HHV-8) is the etiological agent of Kaposi's sarcoma, primary effusion lymphoma, and some forms of multicentric Castleman's disease. Although latent HHV-8 DNA can be detected in B cells from persons with these cancers, there is little information on the replication of HHV-8 in B
A tumor model system of clones of myeloproliferative sarcoma virus (MPV)-transformed rat fibroblasts (NRK) with different growth properties and metastatic potential was studied. The relationship between metastatic behavior and composition of carbohydrate-binding proteins (lectins) was analyzed by

Glycans with Antiviral Activity from Marine Organisms.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
There remains today a critical need for new antiviral agents, particularly in view of the alarming increase in drug resistance and associated issues. The marine environment has been a prolific contributor towards the identification of novel therapeutic agents in the recent few decades. Added to

Differential expression of endogenous sugar-binding proteins (lectins) in murine tumor model systems with metastatic capacity.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
In order to investigate possible differences in sugar binding activities of strongly versus weakly metastatic tumors, sugar-binding molecules (endogenous lectins) of murine tumor cells differing in metastatic capacity were analyzed by affinity chromatography on supports with immobilized sugars or

Prevention of experimental liver metastases by D-galactose.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
The metastasis of malignant tumors from a primary site to near and distant secondary sites is probably the most important event in the pathogenesis of cancer and it accounts for most cancer deaths. Whereas advances in the treatment of primary cancer have led to increased patient survival, metastatic

Isolation and chemical characterization of polysaccharides from Iwatake, Gyrophora esculenta Miyoshi.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
A heteropolysaccharide and a beta-D-glucan were isolated from a lichen, Gyrophora esculenta Miyoshi (Iwatake), by cold water and alkali extractions, respectively. The chemical properties of purified polysaccharides were examined by acid hydrolysis, methylation, and GC-MS. The heteropolysaccharide is

Coley's immunotherapy revived: Innate immunity as a link in priming cancer cells for an attack by adaptive immunity.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
There is no doubt that immunotherapy lies in the spotlight of current cancer research and clinical trials. However, there are still limitations in the treatment response in certain types of tumors largely due to the presence of the complex network of immunomodulatory and immunosuppressive pathways.

DC-SIGN is a receptor for human herpesvirus 8 on dendritic cells and macrophages.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Human herpesvirus 8 (HHV-8) causes Kaposi's sarcoma and pleural effusion lymphoma. In this study, we show that dendritic cell-specific ICAM-3 grabbing nonintegrin (DC-SIGN; CD209) is a receptor for HHV-8 infection of myeloid DCs and macrophages. DC-SIGN was required for virus attachment to these
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