OBJECTIVE
To develop a sensitive HPLC-MS/MS method for the determination of nicacid and its metabolites in human plasma.
METHODS
The assay was conducted with an API 3000 LC-MS/MS system comprising of a Genimi C18 column (50 x 3.00 mm, 3 microm), and an eluate of 0.1% acetic acid-methanol-isopropyl