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panaxynol/סרטן

הקישור נשמר בלוח
מאמריםניסויים קלינייםפטנטים
12 תוצאות

Panaxynol, a natural Hsp90 inhibitor, effectively targets both lung cancer stem and non-stem cells.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Cancer stem-like cells (CSCs) contribute to tumor recurrence and chemoresistance. Hence, strategies targeting CSCs are crucial for effective anticancer therapies. Here, we demonstrate the capacities of the non-saponin fraction of Panax ginseng and its active principle panaxynol to inhibit Hsp90
We investigated the mechanism of action of panaxynol (PAL) extract from the root of Saposhnikovia diviaricata (Turcz.) Schischk for treating acute liver injury caused by lipopolysaccharide (LPS) and D-galactosamine (D-Gal N) in mice. A mouse model of acute liver failure induced by LPS/D-Gal N

Panaxynol, a bioactive component of American ginseng, targets macrophages and suppresses colitis in mice

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Ulcerative colitis has a significant impact on the quality of life for the patients, and can substantially increase the risk of colon cancer in patients suffering long-term. Conventional treatments provide only modest relief paired with a high risk of side effects, while complementary and
Methanol extracts of 36 samples of 21 Umbelliferae plants were screened for polyacetylenic compounds using the ELISA for panaxytriol, and their antiproliferative activity was checked by MTT assay using the tumor cell lines MK-1, HeLa and B16F10. The presence of antiproliferative polyacetylenes was

Induction of apoptosis in human promyelocytic leukemia HL60 cells by panaxynol and panaxydol.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Panaxynol and panaxydol are naturally occurring polyacetylenes, isolated from the lipophilic fractions of Panax notoginseng, that exert anti-proliferative effects against malignant cells. However, to the best of our knowledge, no study concerning the inhibitory effects of the two polyacetylenes on

The first specific antibody against cytotoxic polyacetylenic alcohol, panaxynol.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Antitumor polyacetylenic alcohol, panaxynol, was isolated and purified from a powder of the root of Panax ginseng C.A. Meyer. Panaxynol inhibited the growth of various kinds of cultured tumor cell lines in a dose-dependent manner. In this paper we demonstrated the first specific antibody production

Effect of petroleum ether extract of Panax ginseng roots on proliferation and cell cycle progression of human renal cell carcinoma cells.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Panax ginseng roots have long been used as a medicinal herb in oriental countries. We have investigated anti-proliferative effects of lipid soluble Panax ginseng components on human renal cancer cell lines. Petroleum ether extract of Panax ginseng roots (GX-PE) or its partially purified preparation

Antitrypanosomal properties of Panax ginseng C. A. Meyer: new possibilities for a remarkable traditional drug.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
African trypanosomiasis is still a major health problem in many sub-Saharan countries in Africa. We investigated the effects of three preparations of Panax ginseng, Panax notoginseng, isolated ginsenosides, and the polyacetylene panaxynol on Trypanosoma brucei brucei and the human cancer cell line

Screening of polyacetylenic alcohols in crude drugs using the ELISA for panaxytriol.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Polyacetylenic alcohols such as panaxytriol, panaxynol and panaxydol isolated from the roots of Panax ginseng C. A. MEYER have antiproliferative activity against various cultured tumor cells. Anti-panaxytriol antibody was obtained by immunizing rabbits with panaxytriol-bovine serum albumin

Polyacetylenes from the roots of cultivated-wild ginseng and their cytotoxicity in vitro.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Column chromatographic separation of the roots of cultivated-wild ginseng (Jangnoisam) led to the isolation of seven polyacetylenes (1-7). Their structures were determined by spectroscopic methods to be panaxynol (1), ginsenoyne-A (2), panaxydol (3), 10-methoxy heptadeca-1-ene-4, 6-dyne-3, 9-diol

Quantitative Analyses of the Functional Constituents in SanYangSam and SanYangSanSam.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
UNASSIGNED SanYangSam and SanYangSanSam are traditional Korea-medical herbs that are grown from Panax ginseng C.A. Meyer. In our previous studies, we found that the functional compounds in SanYangSam and SanYangSanSam were different and depended on the type and the cultivation environment of

Molecules from American Ginseng Suppress Colitis through Nuclear Factor Erythroid-2-Related Factor 2

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Ulcerative colitis (UC) is a chronic inflammatory bowel disease that affects millions of people worldwide and increases the risk of colorectal cancer (CRC) development. We have previously shown that American ginseng (AG) can treat colitis and prevent colon cancer in mice. We further fractionated AG
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